Propofol and Perioperative Inflammation

PHASE4CompletedINTERVENTIONAL
Enrollment

79

Participants

Timeline

Start Date

March 31, 2005

Primary Completion Date

December 31, 2005

Study Completion Date

December 31, 2005

Conditions
Inflammation
Interventions
DRUG

propofol

Induction with propofol (1.5 to 2mg/kg) and maintenance of anesthesia with propofol 1% (target controlled infusion with concentration levels of 3-5 ug/ml)

DRUG

Intralipid 10%

Induction of anesthesia with thiopental (3-5mg/kg) and maintenance of anesthesia with isoflurane (end-expired concentration = 0.5%-2.0%) as well as the solvent of propofol 1% (Intralipid 10%; corresponding to a target-controlled infusion of propofol with concentration levels of 3-5ug/ml)

DRUG

Saline

Induction of anesthesia with thiopental (3-5mg/kg) and maintenance of anesthesia with isoflurane (end-expired concentration = 0.5%-2.0%)

Trial Locations (1)

1211

Service of Anesthesiology; Geneva University Hospital, Geneva

All Listed Sponsors
lead

University Hospital, Geneva

OTHER

NCT01115179 - Propofol and Perioperative Inflammation | Biotech Hunter | Biotech Hunter