Effect of Simvastatin and Ezetimibe on Lipid and Inflammation

NACompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

June 30, 2005

Primary Completion Date

May 31, 2006

Study Completion Date

November 30, 2007

Conditions
PrediabetesHypercholesterolemiaInflammationCardiovascular Risk
Interventions
DRUG

Simvastatin

Tablets of simvastatin 20 mg administered once a day for 12 weeks

DRUG

Ezetimibe

Tablets of ezetimibe 10 mg administered once a day for 12 weeks

DRUG

Combination Simvastatin plus Ezetimibe

"Simvastatin 20 mg, once a day, was administered for an additional 12-week period for the subset of individuals who took the initial monotherapy with ezetimibe 10 mg (12 week duration).~Ezetimibe 10 mg, once a day, was administered for an additional 12-week period for the subset of individuals who took the initial monotherapy with simvastatin 20 mg (12 week duration).~This Combination represents the experimental period of the present study."

Trial Locations (1)

04038-002

Hospital do Rim e Hipertensao da UNIFESP, São Paulo

All Listed Sponsors
lead

Federal University of São Paulo

OTHER

NCT01103648 - Effect of Simvastatin and Ezetimibe on Lipid and Inflammation | Biotech Hunter | Biotech Hunter