Cardiovascular Safety of Febuxostat and Allopurinol in Participants With Gout and Cardiovascular Comorbidities (CARES)

PHASE3CompletedINTERVENTIONAL
Enrollment

6,198

Participants

Timeline

Start Date

April 23, 2010

Primary Completion Date

May 15, 2017

Study Completion Date

July 18, 2017

Conditions
Cardiovascular Disease
Interventions
DRUG

Febuxostat

Febuxostat tablets

DRUG

Allopurinol

Allopurinol tablets

Trial Locations (203)

Unknown

Decatur

Dunwoody

Marietta

Norcross

Roswell

Suwanee

Waycross

Honolulu

Boise

Coeur d'Alene

Nampa

Addison

Arlington Heights

Evanston

Evergreen Park

Flossmoor

Melrose Park

Morton

Naperville

Quincy

Rockford

Bloomington

Brownsburg

Lafayette

Valparaiso

Iowa City

Lenexa

Overland Park

Topeka

Wichita

Elizabethtown

Lexington

Owensboro

Paducah

Mer Rouge

Monroe

Shreveport

Biddeford

Rockport

Baltimore

Cumberland

Hagerstown

Lutherville

Wheaton

Brockton

Fall River

Hyannis

Worcester

Ann Arbor

Bingham Farms

Chelsea

Detroit

Flint

Kalamazoo

Lansing

Chaska

Duluth

Edina

Saint Paul

Jackson

Olive Branch

Port Gibson

Clarkson Valley

Hazelwood

Kansas City

Saint Charles

St Louis

Washington

Billings

Butte

Bellevue

Grand Island

Lincoln

Omaha

Henderson

Las Vegas

Reno

Brick

Edison

Oradell

Albuquerque

Las Vegas

Endwell

Freeport

Glens Falls

Mineola

New Windsor

New York

Rochester

West Seneca

Westfield

Asheboro

Cary

Charlotte

Columbia

Greensboro

Huntersville

Lenoir

Monroe

Raleigh

Salisbury

Shelby

Wilmington

Winston-Salem

Fargo

Akron

Centerville

Cincinnati

Columbus

Dayton

Delaware

Franklin

Kettering

Lyndhurst

Marion

Mentor

Middleburg Heights

Toledo

Willoughby Hills

Oklahoma City

Tulsa

Ashland

Bend

Eugene

Portland

Altoona

Bensalem

Bethlehem

Downingtown

Duncansville

Ephrata

Harleysville

Lansdale

McMurray

Philadelphia

Quakertown

Wyomissing

Cumberland

East Providence

Providence

Anderson

Charleston

Columbia

Greenville

Greenwood

Greer

Myrtle Beach

Orangeburg

Pelzer

Simpsonville

Spartanburg

Athens

Chattanooga

Clarksville

Collierville

Fayetteville

Jackson

Kingsport

Memphis

New Tazewell

Bellaire

Carrollton

Dallas

El Paso

Fort Worth

Grapevine

Houston

Irving

McKinney

New Braunfels

Odessa

Pearland

Plano

Richardson

San Antonio

Southlake

Sugar Land

Tomball

Waco

Bountiful

Draper

Salt Lake City

West Jordan

Alexandria

Arlington

Burke

Danville

McLean

Norfolk

Richmond

Salem

Virginia Beach

Port Orchard

Tacoma

Clarksburg

Green Bay

Milwaukee

New Berlin

Oregon

Verona

Waukesha

Weston

Jalisco

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Takeda

INDUSTRY