Efficacy And Safety Study Of Tanezumab Subcutaneous Administration In Osteoarthritis - A Subcutaneous/Intravenous Bridging Study

PHASE3TerminatedINTERVENTIONAL
Enrollment

385

Participants

Timeline

Start Date

March 30, 2010

Primary Completion Date

November 8, 2010

Study Completion Date

February 18, 2011

Conditions
OsteoarthritisArthritisPain
Interventions
BIOLOGICAL

Placebo IV

1 ml of placebo administered SC and IV once every 8 weeks.

BIOLOGICAL

Placebo SC

1 ml of placebo administered SC and IV once every 8 weeks.

BIOLOGICAL

Tanezumab SC

1 ml tanezumab injection SC administered every 8 weeks

BIOLOGICAL

Placebo IV

1 ml placebo administered IV every 8 weeks

BIOLOGICAL

Tanezumab SC

1 ml tanezumab injection SC administered every 8 weeks

BIOLOGICAL

Placebo IV

1ml placebo administered IV every 8 weeks

BIOLOGICAL

Tanezumab SC

1 ml tanezumab injection SC administered every 8 weeks

BIOLOGICAL

Placebo IV

1ml placebo administered IV every 8 weeks

BIOLOGICAL

Tanezumab IV

1 ml tanezumab injection IV administered every 8 weeks

BIOLOGICAL

Placebo SC

1ml placebo administered SC every 8 weeks

Trial Locations (91)

11576

Andrew Porges, MD, PC, Roslyn

16635

Altoona Center for Clinical Research, Duncansville

17042

Lebanon Internal Medicine Associates, Lebanon

19152

Founders Research Corporation, Philadelphia

19610

Clinical Research Center of Reading, LLP, Wyomissing

20003

Office of Cynthia Morgan, MD, Washington D.C.

20902

The Center for Rheumatology and Bone Research, Wheaton

21702

Arthritis Treatment Center, Frederick

22911

Charlottesville Medical Research, Charlottesville

24018

Hypothe Test, LLC, Roanoke

26301

Mountain State Clinical Research, Clarksburg

27407

Greensboro Imaging, Greensboro

27408

Pharmquest, Greensboro

27612

Wake Internal Medicine Consultants, Inc., Raleigh

Wake Research Associates, LLC, Raleigh

29464

Coastal Carolina Research Center, Mt. Pleasant

30189

North Georgia Clinical Research, Woodstock

North Georgia Internal Medicine, Woodstock

32003

Fleming Island Center for Clinical Research, Fleming Island

32205

Westside Center for Clinical Research, Jacksonville

32216

Jacksonville Center for Clinical Research, Jacksonville

33054

Sunshine Research Center, Opa-locka

33710

St. Petersburg Arthritis Center, St. Petersburg

33756

Innovative Research of West Florida, Inc., Clearwater

33777

BayCare Outpatient Imaging at Bardmoor, Largo

33782

DMI Research, Inc., Pinellas Park

34429

Nature Coast Clinical Research, Crystal River

36117

Vaughn H. Mancha, Jr., MD, PC, Montgomery

37604

SoFHA Clinical Research, Johnson City

39402

Arthritis Associates, PLLC, Hattiesburg

40504

Bluegrass Community Research, Inc., Lexington

45245

Community Research, Cincinnati

45246

Sterling Research Group, Ltd., Cincinnati

48098

Troy Internal Medicine, PC, Troy

48103

Ann Arbor Clinical Reserch, Ann Arbor

57702

Health Concepts, Rapid City

59101

Billings Clinic Infusion Center, Billings

Billings Clinic Research Center, Billings

60616

Apex Medical Research, AMR, Inc., Chicago

67203

Professional Research Network of Kansas, LLC, Wichita

67208

Wichita Clinic PA, Wichita

68114

Midwest Minor Medical, Omaha

Quality Clinical Research, Inc., Omaha

68127

Midwest Minor Medical, Omaha

68144

Midwest Minor Medical, Omaha

68516

Physician Research Collaboration, LLC, Lincoln

70006

BenchMark Research, Metairie

73069

LION Research, Norman

73072

McBride Clinic, Norman

73109

Health Research Institute, Oklahoma City

75075

Clinical Investigations of Texas, LLC, Plano

76309

Grayline Clinical Drug Trials, Wichita Falls

76904

Benchmark Research, San Angelo

77005

Westbury Medical Clinic, Houston

77008

Asif Cochinwala, MD, P.A., Houston

77034

Accurate Clinical Research, Houston

77036

Mercury Clinical Research, Houston

Pioneer Research Solutions, Inc, Houston

77058

Accurate Clinical Research Inc, Nassau Bay

77074

Clinical Trial Network, Houston

Houston Institute for Clinical Research, Houston

77093

Little York Medical Center, Houston

77339

Internist Associates of Texas, Kingwood

77479

Pioneer Research Solutions, Inc, Sugar Land

78731

FutureSearch Trials of Neurology, Austin

78745

Tekton Research, Inc., Austin

Tekton Research, Inc, Austin

80110

Colorado Hematology, Englewood

Colorado Orthopedic Consultants, P.C., Englewood

83702

Sonoma Clinical Research, LLC., Boise

Sonora Clinical Research, Boise

84088

Advanced Clinical Research, West Jordan

85029

Redpoint Research, Phoenix

85206

Novara Clinical Research, Mesa

89128

G. Timothy Kelly, MD, Las Vegas

91505

Providence Clinical Research, Burbank

91786

FMC Clinical Trials, Upland

91942

Triwest Research Associates, La Mesa

91950

Synergy Clinical Research Center, National City

92701

Probe Clinical Research Corp., Santa Ana

Trinity Clinical Trials, Santa Ana

92801

Advanced Clinical Research Institute, Anaheim

West Coast Radiology Center, Anaheim

93720

Valley Research, Fresno

95816

Benchmark Research, Sacramento

96814

East-West Medical Research Institute, Honolulu

92037-1233

Allergy and Rheumatology Medical Clinic, Inc., La Jolla

06905

Stamford Therapeutics Consortium, Stamford

02301

Beacon Clinical Research, LLC, Brockton

01610

Clinical Pharmacology Study Group, Worcester

28209-3734

PMG Research of Charlotte, Charlotte

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY