Daptomycin as Antibiotic Prophylaxis of Sternal Wound Infections

PHASE4CompletedINTERVENTIONAL
Enrollment

650

Participants

Timeline

Start Date

November 30, 2008

Primary Completion Date

March 31, 2012

Study Completion Date

March 31, 2012

Conditions
Wound Infection
Interventions
DRUG

Daptomycin

one infusion of 350 mg intraoperatively after disconnection from the heart-lung machine as an add-on to standard antibiotic prophylaxis

DRUG

Cefuroxime

1500 mg intravenous 30min preoperatively during anesthesia and 1500 mg intravenous intraoperatively after disconnection from the heart-lung machine

Trial Locations (1)

Unknown

Hannover Medical School, Department of Cardiothoracic, Transplant and Vascular surgery, Hanover

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Novartis

INDUSTRY

lead

Hannover Medical School

OTHER