4,509
Participants
Start Date
June 2, 2010
Primary Completion Date
August 31, 2017
Study Completion Date
March 26, 2018
Placebo
Administered subcutaneously for up to 5 years
Denosumab
Administered subcutaneously for up to 5 years
Research Site, Dublin
Research Site, Dublin
Research Site, Dublin
Research Site, Tainan City
Research Site, Manila
Research Site, Manila
Research Site, Brussels
Research Site, Budapest
Research Site, Budapest
Research Site, Riga
Research Site, Budapest
Research Site, Brussels
Research Site, Metro Manila
Research Site, Quezon City
Research Site, Budapest
Research Site, Budapest
Research Site, Budapest
Research Site, Brussels
Research Site, Ottignies
Research Site, Ljublijana
Research Site, Sofia
Research Site, Sofia
Research Site, Maribor
Research Site, Antwerp
Research Site, Camperdown
Research Site, Wahroonga
Research Site, Johannesburg
Research Site, Kogarah
Research Site, Caringbah
Research Site, Tweed Heads
Research Site, Wilrijk
Research Site, Edegem
Research Site, Bonheiden
Research Site, Leuven
Research Site, East Melbourne
Research Site, Footscray
Research Site, Parkville
Research Site, Fitzroy
Research Site, Heidelberg
Research Site, Richmond
Research Site, Ringwood East
Research Site, Malvern
Research Site, Bentleigh East
Research Site, Frankston
Research Site, Pietermaritzburg
Research Site, Warrnambool
Research Site, Liepāja
Research Site, Hasselt
Research Site, Wodonga
Research Site, Liège
Research Site, Plovdiv
Research Site, Debrecen
Research Site, Nyíregyháza
Research Site, Namur
Research Site, Veliko Tarnovo
Research Site, Szolnok
Research Site, Bedford Park
Research Site, Daugavpils
Research Site, Yvoir
Research Site, Perth
Research Site, Cebu City
Research Site, Stara Zagora
Research Site, Subiaco
Research Site, Port Elizabeth
Research Site, Szeged
Research Site, Libramont
Research Site, Rousse
Research Site, Vejle
Research Site, Herning
Research Site, Tournai
Research Site, Pécs
Research Site, Cape Town
Research Site, Bruges
Research Site, Ã…rhus C
Research Site, Székesfehérvár
Research Site, Ostend
Research Site, Kortrijk
Research Site, Viborg
Research Site, Zalaegerszeg
Research Site, Ghent
Research Site, Varna
Research Site, Győr
Research Site, Sint-Niklaas
Research Site, Taipei
Research Site, New York
Research Site, New York
Research Site, New York
Research Site, Berlin
Research Site, Berlin
Research Site, Nyack
Research Site, Distrito Federal
Research Site, Belgrade
Research Site, Cádiz
Research Site, Athens
Research Site, Athens
Research Site, East Setauket
Research Site, Córdoba
Research Site, A Coruña
Research Site, A Coruña
Research Site, Poria Eylit
Research Site, Pittsburgh
Research Site, Kota Bharu
Research Site, Girona
Research Site, Hershey
Research Site, Niš
Research Site, Rostock
Research Site, Milan
Research Site, Keelung
Research Site, Bethesda
Research Site, Monza (MB)
Research Site, Columbia
Research Site, Dijon
Research Site, Varese
Research Site, Baltimore
Research Site, Annapolis
Research Site, Jaén
Research Site, Richmond
Research Site, Roanoke
Research Site, Treviglio (BG)
Research Site, Kiel
Research Site, Richlands
Research Site, Brescia
Research Site, Lleida
Research Site, Pátrai
Research Site, High Point
Research Site, Madrid
Research Site, Colima
Research Site, Madrid
Research Site, Madrid
Research Site, Asheville
Research Site, Alcorcón
Research Site, Málaga
Research Site, Columbia
Research Site, Charleston
Research Site, Hilton Head Island
Research Site, Athens
Research Site, Haifa
Research Site, Jacksonville
Research Site, Melbourne
Research Site, Hollywood
Research Site, Bordeaux
Research Site, Coral Springs
Research Site, Fort Lauderdale
Research Site, Boynton Beach
Research Site, Durango
Research Site, Bornova-Izmir
Research Site, Birmingham
Research Site, Ä°zmir
Research Site, Nashville
Research Site, Chattanooga
Research Site, León
Research Site, Grenoble
Research Site, Germantown
Research Site, Santander
Research Site, Jackson
Research Site, Seville
Research Site, Paducah
Research Site, Pachuca
Research Site, Saint-Priest-en-Jarez
Research Site, Parma
Research Site, Columbus
Research Site, Nantes
Research Site, Kfar Saba
Research Site, Cincinnati
Research Site, Recklinghausen
Research Site, Valencia
Research Site, Valencia
Research Site, Bottrop
Research Site, Indianapolis
Research Site, Meldola FC
Research Site, Subang Jaya
Research Site, Ann Arbor
Research Site, Detroit
Research Site, Petah Tikva
Research Site, Angers
Research Site, Zaragoza
Research Site, Toluca
Research Site, Kuala Lumpur
Research Site, Cedar Rapids
Research Site, Bonn
Research Site, Trier
Research Site, Thessaloniki
Research Site, Minneapolis
Research Site, Saint Louis Park
Research Site, Edina
Research Site, Kuala Lumpur
Research Site, Koblenz
Research Site, Thessaloniki
Research Site, Sioux Falls
Research Site, Lille
Research Site, Ancona
Research Site, Frankfurt
Research Site, Niles
Research Site, Putzu City
Research Site, Monterrey
Research Site, Tel Aviv
Research Site, Jefferson City
Research Site, Strasbourg
Research Site, Wichita
Research Site, Hutchinson
Research Site, Mannheim
Research Site, Lincoln
Research Site, Pierre-Bénite
Research Site, Tel Aviv
Research Site, Bari
Research Site, San Giovanni Rotondo FG
Research Site, Heraklion
Research Site, Le Mans
Research Site, Tübingen
Research Site, Jonesboro
Research Site, Tulsa
Research Site, Paris
Research Site, Garland
Research Site, Plano
Research Site, Dallas
Research Site, Dallas
Research Site, Tyler
Research Site, Rehovot
Research Site, Querétaro
Research Site, Houston
Research Site, Houston
Research Site, San Luis Potosí City
Research Site, San Antonio
Research Site, San Antonio
Research Site, Ashkelon
Research Site, Corpus Christi
Research Site, El Paso
Research Site, Denver
Research Site, München
Research Site, München
Research Site, Grand Junction
Research Site, München
Research Site, Hyères
Research Site, Tucson
Research Site, Henderson
Research Site, Los Angeles
Research Site, Los Angeles
Research Site, Palermo
Research Site, Beverly Hills
Research Site, Redondo Beach
Research Site, Torrance
Research Site, Long Beach
Research Site, Jerusalem
Research Site, Erlangen
Research Site, Northridge
Research Site, La Verne
Research Site, Alhambra
Research Site, Anaheim
Research Site, Fullerton
Research Site, Santa Barbara
Research Site, Santa Maria
Research Site, Lancaster
Research Site, Fresno
Research Site, Villejuif
Research Site, Campbell
Research Site, Monaco
Research Site, Seattle
Research Site, Tacoma
Research Site, Moscow
Research Site, Ivanovo
Research Site, Saint Petersburg
Research Site, Saint Petersburg
Research Site, Craiova
Research Site, Timișoara
Research Site, Kazan'
Research Site, Chelyabinsk
Research Site, Sibiu
Research Site, Barnaul
Research Site, Suceava
Research Site, Viña del Mar
Research Site, Temuco
Research Site, Santiago
Research Site, Los Angeles
Research Site, New Haven
Research Site, Boston
Research Site, Danvers
Research Site, Lebanon
Research Site, Denville
Research Site, Hackensack
Research Site, Pawtucket
Research Site, Abilene
Research Site, Dallas
Research Site, Seattle
Research Site, Quilmes
Research Site, Quilmes
Research Site, San Martín
Research Site, Neuquén
Research Site, Provincia de Santa Fe
Research Site, San Miguel de Tucumán
Research Site, Salvador
Research Site, Salvador
Research Site, Curitiba
Research Site, Londrina
Research Site, Porto Alegre
Research Site, Porto Alegre
Research Site, Porto Alegre
Research Site, ItajaÃ-
Research Site, Barretos
Research Site, Santo André
Research Site, São Paulo
Research Site, São Paulo
Research Site, São Paulo
Research Site, Calgary
Research Site, Edmonton
Research Site, Kelowna
Research Site, Victoria
Research Site, Moncton
Research Site, St. John's
Research Site, Sydney
Research Site, Barrie
Research Site, Brampton
Research Site, Greater Sudbury
Research Site, Kingston
Research Site, Kitchener
Research Site, Ottawa
Research Site, Sault Ste. Marie
Research Site, Toronto
Research Site, Toronto
Research Site, Greenfield Park
Research Site, Montreal
Research Site, Montreal
Research Site, Montreal
Research Site, Québec
Research Site, Sherbrooke
Research Site, Brno
Research Site, Brno
Research Site, Chomutov
Research Site, Hořovice
Research Site, Hradec Králové
Research Site, Olomouc
Research Site, Prague
Research Site, Prague
Research Site, Prague
Research Site, Prague
Research Site, Prague
Research Site, Hong Kong
Research Site, New Territories
Research Site, Cork
Research Site, Limerick
Research Site, Waterford
Research Site, Hyderabad
Research Site, Bangalore
Research Site, Ahilyanagar
Research Site, Aurangabad
Research Site, Miraj
Research Site, Mumbai
Research Site, Mumbai
Research Site, Nashik
Research Site, Nashik
Research Site, Pune
Research Site, Jaipur
Research Site, Chennai
Research Site, Madurai
Research Site, Nagoya
Research Site, Nagoya
Research Site, Matsuyama
Research Site, Fukuoka
Research Site, Kitakyushu-shi
Research Site, Kurume-shi
Research Site, Kure-shi
Research Site, Akashi-shi
Research Site, Kagoshima
Research Site, Isehara-shi
Research Site, Kumamoto
Research Site, Kyoto
Research Site, Miyazaki
Research Site, Niigata
Research Site, Kurashiki-shi
Research Site, Osaka
Research Site, Osaka
Research Site, Suita-shi
Research Site, Hidaka-Shi
Research Site, Kitaadachi-gun
Research Site, Suntou-gun
Research Site, Shimotsuke-shi
Research Site, Utsunomiya
Research Site, Chuo-ku
Research Site, Tokyo
Research Site, Tokyo
Research Site, Tokyo
Research Site, Tokyo
Research Site, Mexico City
Research Site, Mexico City
Research Site, Mexico City
Research Site, Amsterdam
Research Site, Bergen op Zoom
Research Site, Breda
Research Site, Capelle aan den IJssel
Research Site, Dordrecht
Research Site, Hoofddorp
Research Site, Leiden
Research Site, Nieuwegein
Research Site, Rotterdam
Research Site, Rotterdam
Research Site, Schiedam
Research Site, Sittard-Geleen
Research Site, The Hague
Research Site, Tiel
Research Site, Tilburg
Research Site, Venlo
Research Site, Lima
Research Site, Lima
Research Site, Lima
Research Site, Gdansk
Research Site, Gdansk
Research Site, Krakow
Research Site, Olsztyn
Research Site, Poznan
Research Site, Rzeszów
Research Site, Szczecin
Research Site, Lisbon
Research Site, Lisbon
Research Site, Porto
Research Site, Porto
Research Site, Santa Maria da Feira
Research Site, Bucharest
Research Site, Bardejov
Research Site, Košice
Research Site, Michalovce
Research Site, Poprad
Research Site, Prešov
Research Site, Spišská Nová Ves
Research Site, Trebišov
Research Site, Groenkloof
Research Site, Pretoria
Research Site, Pretoria
Research Site, Goyang-si, Gyeonggi-do
Research Site, Incheon
Research Site, Seoul
Research Site, Seoul
Research Site, Seoul
Research Site, Badalona
Research Site, Barcelona
Research Site, Barcelona
Research Site, Barcelona
Research Site, Barcelona
Research Site, Sabadell
Research Site, Elche
Research Site, Ankara
Research Site, Ankara
Research Site, Bebington
Research Site, Birmingham
Research Site, Brighton
Research Site, Bristol
Research Site, Cambridge
Research Site, Dorset
Research Site, Guildford
Research Site, Leeds
Research Site, London
Research Site, London
Research Site, Manchester
Research Site, Manchester
Research Site, Newcastle
Research Site, Peterborough
Research Site, Plymouth
Research Site, Poole
Research Site, Portsmouth
Research Site, Sheffield
Research Site, Truro
Lead Sponsor
Collaborators (1)
Daiichi Sankyo
INDUSTRY
Amgen
INDUSTRY