A Study of a New Candidate Vaccine Against Hepatitis C Virus (HCV)

PHASE1CompletedINTERVENTIONAL
Enrollment

41

Participants

Timeline

Start Date

July 31, 2007

Primary Completion Date

August 31, 2010

Study Completion Date

February 28, 2011

Conditions
Hepatitis C
Interventions
BIOLOGICAL

Ad6NSmut; AdCh3NSmut

2 doses Ad6NSmut 5 x 10\^8vp at weeks 0 and 4 and 1 dose AdCh3NSmut 2.5 x 10\^10vp at week 24.

BIOLOGICAL

Ad6NSmut; AdCh3NSmut

2 doses Ad6NSmut 5 x 10\^9vp at weeks 0 and 4 and 1 dose AdCh3NSmut 2.5 x 10\^10vp at week 24.

BIOLOGICAL

Ad6NSmut; AdCh3NSmut

2 doses Ad6NSmut 2.5 x 10\^10vp at weeks 0 and 4 and 1 dose AdCh3NSmut 2.5 x 10\^10vp at week 24.

BIOLOGICAL

AdCh3NSmut; Ad6NSmut

2 doses AdCh3NSmut 5 x 10\^8vp at weeks 0 and 4 and 1 dose Ad6NSmut 2.5 x 10\^10vp at week 24.

BIOLOGICAL

AdCh3NSmut; Ad6NSmut

2 doses AdCh3NSmut 5 x 10\^9vp at weeks 0 and 4 and 1 dose Ad6NSmut 2.5 x 10\^10vp at week 24.

BIOLOGICAL

AdCh3NSmut; Ad6NSmut

2 doses AdCh3NSmut 2.5 x 10\^10vp at weeks 0 and 4 and 1 dose Ad6NSmut 2.5 x 10\^10vp at week 24.

BIOLOGICAL

Ad6NSmut; AdCh3NSmut

1 dose Ad6NSmut 2.5 x 10\^10vp at week 0 and 1 dose AdCh3NSmut 2.5 x 10\^10vp at week 8.

BIOLOGICAL

AdCh3NSmut; Ad6NSmut

1 dose AdCh3NSmut 2.5 x 10\^10vp at week 0 and 1 dose Ad6NSmut 2.5 x 10\^10vp at week 8.

BIOLOGICAL

AdCh3NSmut; Ad6NSmut

1 dose AdCh3NSmut 7.5 x 10\^10vp at week 0 and 1 dose Ad6NSmut 7.5 x 10\^10vp at week 8.

Trial Locations (2)

OX3 7LJ

Centre for Clinical Vaccinology and Tropical Medicine, Oxford

B15 2TH

Wellcome Clinical Research Facility, Queen Elizabeth's Hospital, University Hospital Birmingham NHS Foundation Trust, Birmingham

All Listed Sponsors
collaborator

University of Oxford

OTHER

lead

ReiThera Srl

INDUSTRY

NCT01070407 - A Study of a New Candidate Vaccine Against Hepatitis C Virus (HCV) | Biotech Hunter | Biotech Hunter