Remote Ischaemic Preconditioning for Heart Surgery (RIPHeart-Study)

PHASE3TerminatedINTERVENTIONAL
Enrollment

1,400

Participants

Timeline

Start Date

December 31, 2010

Primary Completion Date

May 31, 2014

Study Completion Date

May 31, 2015

Conditions
Myocardial InjuryMortality
Interventions
PROCEDURE

Remote Ischemic Preconditioning

RIPC will be induced during anesthesia by four 5-min cycles of upper limb ischemia and 5-min reperfusion using a blood-pressure cuff inflated to a pressure 200 mm Hg, whereas the pressure has to be at least 20 mm Hg greater than the systolic arterial pressure measured via the arterial line.

PROCEDURE

Control/sham procedure (blood pressure cuff)

Sham placement of the blood pressure cuff around a dummy arm inflated to a pressure of 200 mm Hg with four cycles of 5 min inflation and 5 min deflation.

Trial Locations (10)

Unknown

University Hospital Aachen (RWTH), Aachen

University Hospital Charite, Berlin

University Hospital Bonn, Bonn

University Hospital Frankfurt/M, Frankfurt/M

University Hospital Goettingen, Göttingen

University Hospital Schleswig-Holstein, Kiel

University Hospital of Schleswig-Holstein, Lübeck

University Hospital Magdeburg, Magdeburg

University Hospital Rostock, Rostock

University Hospital Wuerzburg, Würzburg

All Listed Sponsors
collaborator

German Research Foundation

OTHER

collaborator

Goethe University

OTHER

lead

University Hospital Schleswig-Holstein

OTHER