An Efficacy and Tolerability Study of Topiramate in Participants With Migraine

PHASE4CompletedINTERVENTIONAL
Enrollment

250

Participants

Timeline

Start Date

July 31, 2006

Primary Completion Date

July 31, 2008

Study Completion Date

July 31, 2008

Conditions
Migraine
Interventions
DRUG

Topiramate Standard

Topiramate 25 mg will be administered once daily and the dose will be increased by 25 mg per day at an interval of 1-week up to a dose of 50 mg to 100 mg up to Week 6. A maintenance dose of 50 mg to 100 mg will be administered twice daily up to Week 10 as per Physician's discretion.

DRUG

Topiramate Slow

Topiramate 25 mg will be administered once daily and the dose will be increased by 25 mg per day at an interval of 2-weeks up to a dose of 50 mg to 100 mg up to Week 6. A maintenance dose of 50 mg to 100 mg will be administered twice daily up to Week 10 as per Physician's discretion.

DRUG

Propranolol booster

Propranolol 80 mg will be administered once daily, 40 mg in the morning and 40 mg in the evening up to Week 6.

Trial Locations (6)

Unknown

Busan

Daegu

Kwangjoo

Kyunggi-Do

Seoul

Uijeongbu-si

All Listed Sponsors
lead

Janssen Korea, Ltd., Korea

INDUSTRY

NCT01060111 - An Efficacy and Tolerability Study of Topiramate in Participants With Migraine | Biotech Hunter | Biotech Hunter