72
Participants
Start Date
July 31, 2005
Primary Completion Date
November 30, 2010
Study Completion Date
November 30, 2010
Ramipril
The starting dose of Ramipril will be 2.5 mg once daily and rapidly titrated upward to 5 mg once daily after 5 days if systolic blood pressure is greater than 100 mmHg. After one month the patient will return to clinic for blood pressure check and will be titrated up to 10 mg once daily.
Candesartan cilexetil
The starting dose of Candesartan cilexetil will be 4 mg or 8 mg once daily and doubled every 2 weeks, if systolic blood pressure is greater than 100 mmHg, to a maximum dose of 32 mg once daily. After one month the patient will return to clinic for blood pressure check and will be titrated up to 32 mg once daily.
Allopurinol
The starting dose of Allopurinol is 300 mg daily.
University of Alabama at Birmingham, Birmingham
Collaborators (1)
National Heart, Lung, and Blood Institute (NHLBI)
NIH
AstraZeneca
INDUSTRY
University of Alabama at Birmingham
OTHER