Avastin as an Adjunct to Diode Laser in the Treatment of Neovascular Glaucoma

PHASE2CompletedINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

January 31, 2006

Primary Completion Date

April 30, 2008

Study Completion Date

April 30, 2008

Conditions
Neovascular Glaucoma
Interventions
PROCEDURE

Diode laser cyclophotocoagulation enhanced by intravitreal injection of Avastin

The operative procedure involved retro-bulbar anesthesia, draping the patient in an aseptic manner, introduction of an eye speculum, 30 laser shots over 270 degrees of the circumference of the limbus. For our study we used the Iris Diode laser machine, the G-probe and we adjusted the settings for 2500 millisecond duration and the 3000 milli-joule and reduced the power progressively until just below the energy level that produced a pop.then after applying the laser, we performed a paracentesis with a 27 gauge needle to soften the globe, followed by intravitreal injection of the Avastin from a site 3.5 millimeter posterior to the limbus. The dose we administered was one milligram of bevacizumab (0.04 mL of 25 mg/mL).

Trial Locations (1)

11451

Kasr El-Ainy hospital, Cairo university,ophthalmology departement, Cairo

All Listed Sponsors
collaborator

AL-Nour Eye Hospital

OTHER

collaborator

Kasr El Aini Hospital

OTHER

lead

Cairo University

OTHER

NCT01051583 - Avastin as an Adjunct to Diode Laser in the Treatment of Neovascular Glaucoma | Biotech Hunter | Biotech Hunter