Efficacy, Safety, and Tolerability of Aclidinium Bromide in the Treatment of Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-38)

PHASE3CompletedINTERVENTIONAL
Enrollment

544

Participants

Timeline

Start Date

March 31, 2009

Primary Completion Date

June 30, 2011

Study Completion Date

June 30, 2011

Conditions
Chronic Obstructive Pulmonary Disease
Interventions
DRUG

Aclidinium bromide

Aclidinium bromide 200 μg, oral inhalation twice per day 12 weeks of treatment. At week 12, patients who were on Aclidinium bromide 200 μg will receive open label 400µg aclidinium bromide for 40 weeks of treatment.

DRUG

Placebo

Dose-matched placebo, oral inhalation twice per day for 12 weeks. At week 12, patients who were on placebo will receive open label 400 µg aclidinium bromide for 40 weeks of treatment

Trial Locations (112)

10028

Forest Investigative Site 1425, New York

10538

Forest Investigative Site 1489, Larchmont

13212

Forest Investigative Site 1373, North Syracuse

15221

Forest Investigative Site 1510, Pittsburgh

16508

Forest Investigative Site 1423, Erie

16684

Forest Investigative Site 1449, Tipton

19053

Forest Investigative Site 1428, Feasterville

19107

Forest Investigative Site 1443, Philadelphia

19426

Forest Investigative Site 1377, Collegeville

21201

Forest Investigative Site 1412, Baltimore

21901

Forest Investigative Site 1518, North East

23294

Forest Investigative Site 1358, Richmond

23502

Forest Investigative Site 1404, Norfolk

24210

Forest Investigative Site 1480, Abingdon

24501

Forest Investigative Site 1402, Lynchburg

27262

Forest Investigative Site 1366, High Point

28277

Forest Investigative Site 1392, Charlotte

29201

Forest Investigative Site 1144, Columbia

29379

Forest Investigative Site 1450, Union

29615

Forest Investigative Site 1506, Grenville

29640

Forest Investigative Site 1517, Easley

30046

Forest Investigative Site 1528, Lawrenceville

30328

Forest Investigative Site 1386, Atlanta

30701

Forest Investigative Site 1411, Calhoun

32129

Forest Investigative Site 1376, Port Orange

32132

Forest Investigative Site 1516, Edgewater

32789

Forest Investigative Site 1185, Winter Park

33021

Forest Investigative Site 1403, Hollywood

33032

Forest Investigative Site 1485, Homestead

33126

Forest Investigative Site 1352, Miami

33143

Forest Investigative Site 1372, South Miami

33756

Forest Investigative Site 1364, Clearwater

34110

Forest Investigative Site 1391, Naples

34655

Forest Investigative Site 1407, Trinity

35128

Forest Investigative Site 1353, Pell City

35209

Forest Investigative Site 1493, Birmingham

35233

Forest Investigative Site 1419, Birmingham

35662

Forest Investigative Site 1413, Muscle Shoals

37337

Forest Investigative Site 1526, Fayetteville

37909

Forest Investigative Site 1356, Knoxville

37920

Forest Investigative Site 1417, Knoxville

41701

Forest Investigative Site 1090, Hazard

42101

Forest Investigative Site 2033, Bowling Green

43209

Forest Investigative Site 1361, Columbus

43213

Forest Investigative Site 1433, Columbus

43608

Forest Investigative Site 1530, Toledo

43701

Forest Investigative Site 1393, Zanesville

45227

Forest Investigative Site 1136, Cincinnati

45245

Forest Investigative Site 1371, Cincinnati

46011

Forest Investigative Site 1479, Anderson

46256

Forest Investigative Site 1441, Indianapolis

46617

Forest Investigative Site 1149, South Bend

47714

Forest Investigative Site 2022, Evansville

48085

Forest Investigative Site 1487, Troy

48118

Forest Investigative Site 1405, Chelsea

48152

Forest Investigative Site 0889, Livonia

52240

Forest Investigative Site 1406, Iowa City

55403

Forest Investigative Site 1124, Minneapolis

55432

Forest Investigative Site 1527, Fridley

55904

Forest Investigative Site 1118, Rochester

58435

Forest Investigative Site 1128, Edina

59808

Forest Investigative Site 1400, Missoula

60007

Forest Investigative Site 1385, Elk Grove Village

62269

Forest Investigative Site 1409, O'Fallon

63141

Forest Investigative Site 1399, St Louis

66606

Forest Investigative Site 1080, Topeka

68005

Forest Investigative Site 1354, Bellevue

68025

Forest Investigative Site 1476, Fremont

68114

Forest Investigative Site 1363, Omaha

68123

Forest Investigative Site 1367, Bellevue

68130

Forest Investigative Site 1390, Omaha

68134

Forest Investigative Site 1422, Omaha

70115

Forest Investigative Site 1430, New Orleans

70119

Forest Investigative Site 1446, New Orleans

70584

Forest Investigative Site 1360, Sunset

73112

Forest Investigative Site 1362, Oklahoma City

75093

Forest Investigative Site 1426, Plano

76012

Forest Investigative Site 1440, Arlington

76054

Forest Investigative Site 1357, Hurst

77074

Forest Investigative Site 1375, Houston

77079

Forest Investigative Site 1444, Houston

77083

Forest Investigative Site 1401, Houston

77375

Forest Investigative Site 1410, Tomball

77479

Forest Investigative Site 1381, Houston

78756

Forest Investigative Site 1494, Austin

79106

Forest Investigative Site 1389, Amarillo

80401

Forest Investigative Site 1380, Golden

81001

Forest Investigative Site 1447, Pueblo

83814

Forest Investigative Site 0679, Coeur d'Alene

85018

Forest Investigative Site 1379, Phoenix

87108

Forest Investigative Site 1486, Albuquerque

89014

Forest Investigative Site 1359, Henderson

89123

Forest Investigative Site 1355, Las Vegas

90274

Forest Investigative Site 1424, Rolling Hill Estates

90505

Forest Investigative Site 1374, Torrance

90723

Forest Investigative Site 1388, Paramount

91950

Forest Investigative Site 1451, National City

92083

Forest Investigative Site 1331, Vista

92120

Forest Investigative Site 1418, San Diego

Forest Investigative Site 2009, San Diego

92835

Forest Investigative Site 2065, Fullerton

95817

Forest Investigative Site 1427, Sacramento

97504

Forest Investigative Site 2018, Medford

Forest Investigative Site 2043, Medford

98405

Forest Investigative Site 0988, Tacoma

02301

Forest Investigative Site 1442, Brockton

02720

Forest Investigative Site 1421, Fall River

02747

Forest Investigative Site 1029, North Dartmouth

02919

Forest Investigative Site 1445, Johnston

02865

Forest Investigative Site 1477, Lincoln

V5Z 4E1

Forest Investigative Site 1177, Vancouver

N8X 5A6

Forest Investigative Site 0969, Windsor

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY