Medication Effects on Periurethral Sensation,Urethral Sphincter Activity and Pressure Flow Parameters

NACompletedINTERVENTIONAL
Enrollment

56

Participants

Timeline

Start Date

April 30, 2010

Primary Completion Date

April 30, 2011

Study Completion Date

April 30, 2011

Conditions
Urethral Sphincter Activity
Interventions
DRUG

Pseudoephedrine

Pseudoephedrine ER 120 mg by mouth once daily for 2 weeks

DRUG

Tamsulosin

Tamsulosin 0.4mg by mouth daily for 2 weeks

DRUG

Imipramine

Imipramine 25mg daily by mouth for 2 weeks

DRUG

Cyclobenzaprine

Cyclobenzaprine 10mg daily by mouth for 2 weeks

DRUG

Lactose capsule

Lactose capsule 1 by mouth daily for 2 weeks

DRUG

Solifenacin

Solifenacin 5mg by mouth daily for 2 weeks

Trial Locations (1)

35233

University of Alabama at Birmingham, The Kirklin Clinic, Birmingham

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Astellas Pharma Inc

INDUSTRY

lead

University of Alabama at Birmingham

OTHER