Cantharidin-induced Skin Blister for Testing Anti-inflammatory Effects of Macrolides

PHASE1CompletedINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

June 4, 2009

Primary Completion Date

November 27, 2009

Study Completion Date

November 27, 2009

Conditions
Inflammation
Interventions
OTHER

Cantharidin

Cantharone topical liquid containing 0.7% cantharidin (blistering agent) is applied as 25 µL of 0.1% cantharone solution in acetone

DRUG

Azithromycin

Zithromax (250 mg oral capsule).

DRUG

Placebo

Matching placebo

Trial Locations (1)

CB2 0QQ

GSK Investigational Site, Cambridge

Sponsors

Lead Sponsor

All Listed Sponsors
lead

GlaxoSmithKline

INDUSTRY