Evaluation of Antiplatelet Drug Resistance in Taiwanese With VASP & Platelet Mapping ™ Assay

PHASE4UnknownINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

May 31, 2008

Primary Completion Date

October 31, 2010

Study Completion Date

October 31, 2010

Conditions
30 Healthy People
Interventions
DRUG

Clopidogrel and proton pump inhibitors

"baseline detection --\> clopidogrel 75 mg PO QD for 1 week --\> clopidogrel 75 mg plus rabeprazole 20mg PO QD for 1 week --\> clopidogrel 75 mg PO QD for 1 week (wash-out phase) --\> clopidogrel 75 mg plus pantoprazole 40mg PO QD for 1 week --\> clopidogrel 75 mg PO QD for 1 week (wash-out phase) --\> clopidogrel 75 mg plus esomeprazole 40mg PO QD for 1 week --\>~1 week washout --\> aspirin 100mg PO QD for 1 week"

Trial Locations (1)

100

RECRUITING

National Taiwan University Hospital, Taipei

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Haemonetics Corporation

INDUSTRY

lead

National Taiwan University Hospital

OTHER