59
Participants
Start Date
May 31, 2007
Primary Completion Date
September 30, 2011
Study Completion Date
September 30, 2011
Placebo dispensed to subject.
Placebo for 11 days, (one pill at bedtime on nights 1 and 2, 2 pills at bedtime on nights 3-10, and 1 pill at bedtime on night 11, then D/C). They return to the Sleep Lab for polysomnography on nights 8 - 10 of medication so their sleep data can be compared.
Gabapentin dispensed to subject.
After spending 3 baseline nights in the UM Sleep Lab, alcohol dependent subjects are randomized to receive either gabapentin or placebo for 11 days. (1 pill (600 mg) at bedtime on nights 1 and 2, 2 pills (totalling 1200 mg) at bedtime on nights 3-10, and 1 pill (600 mg) at bedtime on night 11, then D/C). On nights 8 - 10 of medication, subjects return to the lab and sleep 3 more nights with the same procedures.
University of Michigan Health System, Ann Arbor
National Institutes of Health (NIH)
NIH
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Dr. Kirk Brower
OTHER