Blood Management in Orthopedic Surgery

PHASE4CompletedINTERVENTIONAL
Enrollment

2,598

Participants

Timeline

Start Date

May 31, 2004

Primary Completion Date

September 30, 2009

Study Completion Date

September 30, 2009

Conditions
Osteoarthritis
Interventions
OTHER

erythropoietin and cell saver

weekly 40.000 IU s.c. for 4 weeks pre-operatively; use of cell saver includes intra- and post-operative drainage and reinfusion

DRUG

erythropoietin

weekly 40.000 IU s.c. for 4 weeks pre-operatively

DEVICE

OrthoPAT

for intra- and post-operative re-infusion of autologous wound blood

DEVICE

Post-operative drain device

For post-operative re-infusion of unwashed wound blood

OTHER

Erythropoietin and OrthoPAT

weekly 40.000 IU s.c. for 4 weeks pre-operatively

OTHER

Erythropoietin and drain device

weekly 40.000 IE s.c.for 4 weeks pre-operatively; drain use in post-operative period

DEVICE

OrthoPAT

For intra- and post-operative reinfusion of autologous blood

Trial Locations (4)

Unknown

Slotervaart Hospital, Amsterdam

Albert Schweitzer Hospital, Dordrecht

Groene Hart Hospital, Gouda

LUMC, Leiden

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

ZonMw: The Netherlands Organisation for Health Research and Development

OTHER

collaborator

Roche BV Netherlands

UNKNOWN

collaborator

Haemonetics Corporation

INDUSTRY

lead

Sanquin Research & Blood Bank Divisions

OTHER