The FIRSTT: Comparing MRgFUS(MR-guided Focused Ultrasound) Versus UAE (Uterine Artery Embolization)for Uterine Fibroids.

PHASE4CompletedINTERVENTIONAL
Enrollment

56

Participants

Timeline

Start Date

April 29, 2010

Primary Completion Date

December 31, 2016

Study Completion Date

December 31, 2017

Conditions
Symptomatic Uterine LeiomyomasFibroidsUterine FibroidsMyomas
Interventions
PROCEDURE

Focused ultrasound (MRgFUS)

MRgFUS treatment will take place in a MRI machine and powerful ultrasound waves go through the abdominal wall to destroy the fibroid or fibroids. No incision is made during this treatment and light sedation is required. There are certain fibroids that may not be treated with this technique and there is no treatment of normal uterine tissue.ough the abdominal wall to destroy the fibroid.

PROCEDURE

Uterine artery embolization (UAE)

UAE treatment takes place on a regular x-ray machine. A small incision is made where the leg meets the trunk and a small tube is used to use very small pellets to block off the blood supply to the entire uterus. Sedation is used. Most fibroids are treated with this technique and normal uterine tissue is also affected.

Trial Locations (3)

27705

Duke University Health System, Durham

55905

Mayo Clinic, Rochester

94116

University of California, San Francisco, San Francisco

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

lead

Mayo Clinic

OTHER

NCT00995878 - The FIRSTT: Comparing MRgFUS(MR-guided Focused Ultrasound) Versus UAE (Uterine Artery Embolization)for Uterine Fibroids. | Biotech Hunter | Biotech Hunter