Role of Neural and Hormonal Regulation Factors on Insulin Secretion After Gastric Bypass Surgery

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

October 31, 2009

Primary Completion Date

August 31, 2026

Study Completion Date

August 31, 2027

Conditions
Post BariatricsurgeryHypoglycemia
Interventions
DRUG

Exendin-(9-39)

A physiological study to evaluate the role of GLP-1 signaling in glucose tolerance and insulin secretion

DRUG

Atropine

A physiological study to evaluate the effect of neural activation on insulin secretion and glucose metabolism

DRUG

GLP-1 and GIP

A physiological study to evaluate the beta-cell sensitivity to different doses of exogenous gut hormones

Trial Locations (2)

78207

RECRUITING

Texas Diabetes Institute - University Health System, San Antonio

78229

RECRUITING

South Texas Veterans Health Care System, San Antonio

All Listed Sponsors
lead

The University of Texas Health Science Center at San Antonio

OTHER

NCT00992901 - Role of Neural and Hormonal Regulation Factors on Insulin Secretion After Gastric Bypass Surgery | Biotech Hunter | Biotech Hunter