NCT00992901View on ClinicalTrials.gov

Role of Neural and Hormonal Regulation Factors on Insulin Secretion After Gastric Bypass Surgery

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

October 31, 2009

Primary Completion Date

August 31, 2026

Study Completion Date

August 31, 2027

Conditions
Post BariatricsurgeryHypoglycemia
Interventions
DRUG

Exendin-(9-39)

A physiological study to evaluate the role of GLP-1 signaling in glucose tolerance and insulin secretion

DRUG

Atropine

A physiological study to evaluate the effect of neural activation on insulin secretion and glucose metabolism

DRUG

GLP-1 and GIP

A physiological study to evaluate the beta-cell sensitivity to different doses of exogenous gut hormones

Trial Locations (2)

78207

RECRUITING

Texas Diabetes Institute - University Health System, San Antonio

78229

RECRUITING

South Texas Veterans Health Care System, San Antonio

All Listed Sponsors
lead

The University of Texas Health Science Center at San Antonio

OTHER