Using Allopurinol to Relieve Symptoms in Patients With Heart Failure and High Uric Acid Levels

PHASE2CompletedINTERVENTIONAL
Enrollment

253

Participants

Timeline

Start Date

May 31, 2010

Primary Completion Date

December 31, 2013

Study Completion Date

June 30, 2014

Conditions
Heart FailureElevated Serum Uric Acid
Interventions
DRUG

allopurinol

Allopurinol 300 mg daily for one week, then 600 mg daily to complete 24 weeks.

DRUG

sugar pill

Matching placebo 300 mg daily for one week, then 600 mg daily to complete 24 weeks.

Trial Locations (10)

44106

University Hospitals-Case Medical Center, Cleveland

Unknown

Morehouse School of Medicine, Atlanta

Harvard University, Boston

University of Minnesota, Minneapolis

Mayo Clinic, Rochester

Duke University Medical Center, Durham

Baylor College of Medicine, Houston

Univ. of Utah Health Sciences Center, Salt Lake City

University of Vermont, Burlington

University of Montreal, Montreal PQ

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Duke University

OTHER

NCT00987415 - Using Allopurinol to Relieve Symptoms in Patients With Heart Failure and High Uric Acid Levels | Biotech Hunter | Biotech Hunter