A Drug-Food Interaction Study Between Colchicine and Grapefruit Juice

PHASE1CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

September 30, 2008

Primary Completion Date

October 31, 2008

Study Completion Date

October 31, 2008

Conditions
Pharmacokinetics
Interventions
DRUG

Colchicine

A single dose of 0.6 mg colchicine administered alone at 7:15 a.m. on Day 1

OTHER

Grapefruit Juice

240 mL of grapefruit juice ingested twice daily at 7:15 a.m. and 7:15 p.m. on Days 15 to 18.

DRUG

Colchicine

A single dose of 0.6 mg colchicine administered with grapefruit juice at 7:15 a.m. on Day 18 after an overnight fast of at least 10 hours.

Trial Locations (1)

58104

PRACS Institute, Ltd. - Cetero Research, Fargo

All Listed Sponsors
lead

Mutual Pharmaceutical Company, Inc.

INDUSTRY

NCT00984009 - A Drug-Food Interaction Study Between Colchicine and Grapefruit Juice | Biotech Hunter | Biotech Hunter