Drug-Drug Interaction Between Colchicine and Ritonavir

PHASE1CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

July 31, 2008

Primary Completion Date

August 31, 2008

Study Completion Date

August 31, 2008

Conditions
Pharmacokinetics
Interventions
DRUG

Colchicine

A single dose of colchicine 0.6 mg administered alone at 7:00 a.m. on Day 1 after an overnight fast of at least 10 hours.

DRUG

Ritonavir

One 100 mg ritonavir capsule administered twice daily at 7:00 a.m. and 7:00 p.m. on Days 15 to 18 without regard to meals, then along with colchicine at 7:00 a.m. on Day 19 after an overnight fast of at least 10 hours; final dose of 100 mg ritonavir administered at 7:00 p.m. on Day 19

DRUG

Colchicine

A single dose of colchicine 0.6 mg administered along with ritonavir at 7:00 a.m. on Day 19

Trial Locations (1)

56721

PRACS Institute, Ltd. - Cetero Research, East Grand Forks

All Listed Sponsors
lead

Mutual Pharmaceutical Company, Inc.

INDUSTRY

NCT00983515 - Drug-Drug Interaction Between Colchicine and Ritonavir | Biotech Hunter | Biotech Hunter