Immune-based Therapy Pilot Study for the Treatment of Primary HIV Infection (PHI-IMD).

PHASE4CompletedINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

March 31, 2005

Primary Completion Date

November 30, 2014

Study Completion Date

November 30, 2014

Conditions
HIV
Interventions
DRUG

HAART

"Patients assigned to this arm will receive Trizivir and kaletra. After the first 9 months of HAART, all patients will stop HAART until HIV viral load in plasma became detectable (\>200 copies/mL). Then, they will re-start HAART plus low doses of IL-2 during 2 months.~All patients will be followed-up during 1 year."

DRUG

HAART + Immunotherapy

"Patients assigned to this arm will receive Trizivir + Kaletra + cyclosporin A during the first two months. This group also will receive GM-CSF plus pegylated-interferon-alpha until HIV viral load in plasma became detectable (\>200 copies/mL). Then, they will re-start HAART plus low doses of IL-2 during 2 months. At this moment they will stop HAART.~All patients will be followed-up during 1 year."

Trial Locations (1)

08036

Hospital Clinic de Barcelona, Barcelona

All Listed Sponsors
lead

Juan A. Arnaiz

OTHER

NCT00979706 - Immune-based Therapy Pilot Study for the Treatment of Primary HIV Infection (PHI-IMD). | Biotech Hunter | Biotech Hunter