NCT00977600View on ClinicalTrials.gov

A Study of Glyceryl Tri-(4-phenylbutyrate) (GT4P)

PHASE1CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

March 31, 2005

Study Completion Date

July 31, 2005

Conditions
Healthy
Interventions
DRUG

HPN-100

HPN-100 is a triglyceride that has a similar mechanism of action as Buphenyl. It is a liquid with minimal taste and odor. HPN-100 is broken down to phenylbutyric acid (PBA). PBA is converted to phenyl acetic acid (PAA) that is the active metabolite. Three teaspoons of HPN-100 (\~17.4mL) delivers equivalent amount of PBA that 40 tablets of NaPBA do.

DRUG

Ammonul

DRUG

Buphenyl

Trial Locations (1)

61011

Medical Sanitary Division #2, Kharkiv

Sponsors

Lead Sponsor

Amgen
All Listed Sponsors
collaborator

Ucyclyd Pharma, Inc.

OTHER

lead

Amgen

INDUSTRY

NCT00977600 - A Study of Glyceryl Tri-(4-phenylbutyrate) (GT4P) | Biotech Hunter | Biotech Hunter