NCT00968968 - Continued HER2 Suppression With Lapatinib Plus Trastuzumab Versus Trastuzumab Alone | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

January 20, 2010

Primary Completion Date

February 21, 2014

Study Completion Date

March 30, 2018

Conditions

Cancer

Interventions

DRUG

Lapatinib

Oral Lapatinib 1000 mg once daily. Lapatinib was a small molecule, reversible inhibitor targeting HER2 tyrosine kinase receptor.

BIOLOGICAL

Trastuzumab

IV Trastuzumab 6 mg/kg every three weeks. Trastuzumab was a humanized, monoclonal antibody directed against the extracellular domain of the HER2 tyrosine kinase receptor.

Trial Locations (116)

19001

Novartis Investigative Site, Abington

19087

Novartis Investigative Site, Radnor

19106

Novartis Investigative Site, Philadelphia

20155

Novartis Investigative Site, Gainesville

20176

Novartis Investigative Site, Leesburg

20910

Novartis Investigative Site, Silver Spring

21044

Novartis Investigative Site, Columbia

22031

Novartis Investigative Site, Fairfax

22205

Novartis Investigative Site, Arlington

23185

Novartis Investigative Site, Williamsburg

23320

Novartis Investigative Site, Chesapeake

23456

Novartis Investigative Site, Virginia Beach

23502

Novartis Investigative Site, Norfolk

23606

Novartis Investigative Site, Newport News

23666

Novartis Investigative Site, Hampton

27403

Novartis Investigative Site, Greensboro

27518

Novartis Investigative Site, Cary

27607

Novartis Investigative Site, Raleigh

27614

Novartis Investigative Site, Raleigh

27889

Novartis Investigative Site, Washington

27909

Novartis Investigative Site, Elizabeth City

30901

Novartis Investigative Site, Augusta

30909

Novartis Investigative Site, Augusta

31021

Novartis Investigative Site, Dublin

33021

Novartis Investigative Site, Hollywood

34655

Novartis Investigative Site, New Port Richey

34667

Novartis Investigative Site, Hudson

46526

Novartis Investigative Site, Goshen

46545

Novartis Investigative Site, Mishawaka

48126

Novartis Investigative Site, Dearborn

48183

Novartis Investigative Site, Brownstown

48202

Novartis Investigative Site, Detroit

48322

Novartis Investigative Site, West Bloomfield

55102

Novartis Investigative Site, Saint Paul

55109

Novartis Investigative Site, Maplewood

55125

Novartis Investigative Site, Woodbury

55337

Novartis Investigative Site, Burnsville

55404

Novartis Investigative Site, Minneapolis

55432

Novartis Investigative Site, Fridley

55433

Novartis Investigative Site, Coon Rapids

55435

Novartis Investigative Site, Edina

59102

Novartis Investigative Site, Billings

60005

Novartis Investigative Site, Arlington Heights

60025

Novartis Investigative Site, Glenview

60035

Novartis Investigative Site, Highland Park

60076

Novartis Investigative Site, Skokie

60190

Novartis Investigative Site, Winfield

60201

Novartis Investigative Site, Evanston

60435

Novartis Investigative Site, Joliet

60611

Novartis Investigative Site, Chicago

60714

Novartis Investigative Site, Niles

61615

Novartis Investigative Site, Peoria

61636

Novartis Investigative Site, Peoria

61637

Novartis Investigative Site, Peoria

65109

Novartis Investigative Site, Jefferson City

65201

Novartis Investigative Site, Columbia

75042

Novartis Investigative Site, Garland

75075

Novartis Investigative Site, Plano

75093

Novartis Investigative Site, Plano

75230

Novartis Investigative Site, Dallas

76022

Novartis Investigative Site, Bedford

76051

Novartis Investigative Site, Grapevine

76104

Novartis Investigative Site, Fort Worth

76132

Novartis Investigative Site, Fort Worth

77024

Novartis Investigative Site, Houston

77701

Novartis Investigative Site, Beaumont

78028

Novartis Investigative Site, Kerrville

78217

Novartis Investigative Site, San Antonio

79761

Novartis Investigative Site, Odessa

79902

Novartis Investigative Site, El Paso

79915

Novartis Investigative Site, El Paso

84010

Novartis Investigative Site, Bountiful

84041

Novartis Investigative Site, Layton

84094

Novartis Investigative Site, Sandy City

84102

Novartis Investigative Site, Salt Lake City

84106

Novartis Investigative Site, Salt Lake City

84604

Novartis Investigative Site, Provo

85202

Novartis Investigative Site, Mesa

85206

Novartis Investigative Site, Mesa

85224

Novartis Investigative Site, Chandler

85297

Novartis Investigative Site, Gilbert

85724

Novartis Investigative Site, Tucson

86001

Novartis Investigative Site, Flagstaff

86336

Novartis Investigative Site, Sedona

89052

Novartis Investigative Site, Henderson

89074

Novartis Investigative Site, Henderson

89128

Novartis Investigative Site, Las Vegas

89148

Novartis Investigative Site, Las Vegas

89169

Novartis Investigative Site, Las Vegas

90211

Novartis Investigative Site, Beverly Hills

90813

Novartis Investigative Site, Long Beach

92037

Novartis Investigative Site, La Jolla

92835

Novartis Investigative Site, Fullerton

93309

Novartis Investigative Site, Bakersfield

93454

Novartis Investigative Site, Santa Maria

94806

Novartis Investigative Site, San Pablo

98003

Novartis Investigative Site, Federal Way

98026

Novartis Investigative Site, Edmonds

98104

Novartis Investigative Site, Seattle

98133

Novartis Investigative Site, Seattle

98332

Novartis Investigative Site, Gig Harbor

98372

Novartis Investigative Site, Puyallup

98405

Novartis Investigative Site, Tacoma

98499

Novartis Investigative Site, Lakewood

92093-0987

Novartis Investigative Site, La Jolla

90095- 7187

Novartis Investigative Site, Los Angeles

92103-8411

Novartis Investigative Site, San Diego

02114

Novartis Investigative Site, Boston

02215

Novartis Investigative Site, Boston

79606-5208

Novartis Investigative Site, Abilene

78258-3912

Novartis Investigative Site, San Antonio

84157-7000

Novartis Investigative Site, Murray

B3H 1V7

Novartis Investigative Site, Halifax

L6R 3J7

Novartis Investigative Site, Brampton

L1G 2B9

Novartis Investigative Site, Oshawa

G5L 5T1

Novartis Investigative Site, Rimouski