94
Participants
Start Date
November 30, 2009
Primary Completion Date
August 31, 2012
Study Completion Date
May 14, 2018
Single-fraction stereotactic body radiation therapy (SBRT)
34 Gy in 1 fraction to the prescription line at the edge of the planning target volume (PTV). The maximum dose must exist within the PTV, and the prescription isodose surface must be ≥ 60% and \< 90% of the maximum dose. 99% of the PTV must receive a minimum of 90% of the prescription dose. The maximum dose to any point ≥ 2 cm away from the PTV in any direction must be at least \< 50% of the prescription dose. The percent of the lungs (excluding PTV) receiving 20 Gy or more must be \< 10%.
Multiple-fraction stereotactic body radiation therapy (SBRT)
48 Gy in four 12 Gy fractions to the prescription line at the edge of the planning target volume (PTV). Treatments are given on 4 consecutive calendar days, but at least 18 hours apart. The maximum dose must exist within the PTV, and the prescription isodose surface must be ≥ 60% and \< 90% of the maximum dose. 99% of the PTV must receive a minimum of 90% of the prescription dose. The maximum dose to any point ≥ 2 cm away from the PTV in any direction must be at least \< 50% of the prescription dose. The percent of the lungs (excluding PTV) receiving 20 Gy or more must be \< 10%.
James P. Wilmot Cancer Center at University of Rochester Medical Center, Rochester
Dale and Frances Hughes Cancer Center at Pocono Medical Center, East Stroudsburg
INOVA Alexandria Hospital, Alexandria
Baptist Cancer Institute - Jacksonville, Jacksonville
M.D. Anderson Cancer Center at Orlando, Orlando
James Graham Brown Cancer Center at University of Louisville, Louisville
Flower Hospital Cancer Center, Sylvania
Cleveland Clinic Taussig Cancer Center, Cleveland
Memorial Hospital of South Bend, South Bend
Parkview Regional Cancer Center at Parkview Health, Fort Wayne
Josephine Ford Cancer Center at Henry Ford Hospital, Detroit
Great Lakes Cancer Institute at McLaren Regional Medical Center, Flint
Medical College of Wisconsin Cancer Center, Milwaukee
Veterans Affairs Medical Center - Milwaukee, Milwaukee
OSF St. Francis Medical Center, Peoria
Community Cancer Center, Normal
Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis, St Louis
CCOP - Kansas City, Kansas City
University of Colorado Cancer Center at UC Health Sciences Center, Aurora
UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco
Alta Bates Summit Comprehensive Cancer Center, Berkeley
Auburn Radiation Oncology, Auburn
Mercy Cancer Center at Mercy San Juan Medical Center, Carmichael
Radiation Oncology Centers - Cameron Park, Cameron Park
Robert H. Lurie Comprehensive Cancer Center at Northwestern University, Chicago
Advocate Lutheran General Cancer Care Center, Park Ridge
Lucille P. Markey Cancer Center at University of Kentucky, Lexington
Roswell Park Cancer Institute, Buffalo
Stony Brook University Cancer Center, Stony Brook
Case Comprehensive Cancer Center, Cleveland
Providence Cancer Center at Providence Portland Medical Center, Portland
Geisinger Cancer Institute at Geisinger Health, Danville
Penn State Hershey Cancer Institute at Milton S. Hershey Medical Center, Hershey
M. D. Anderson Cancer Center at University of Texas, Houston
Virginia Commonwealth University Massey Cancer Center, Richmond
Grand River Regional Cancer Centre at Grand River Hospital, Kitchener
Princess Margaret Hospital, Toronto
McGill Cancer Centre at McGill University, Montreal
Collaborators (1)
National Cancer Institute (NCI)
NIH
NRG Oncology
OTHER
Radiation Therapy Oncology Group
NETWORK