Trial to Assess Lacosamide as the First add-on Anti-epileptic Drug Treatment in Patients With Partial-onset Seizures

PHASE4CompletedINTERVENTIONAL
Enrollment

461

Participants

Timeline

Start Date

August 31, 2009

Primary Completion Date

April 30, 2013

Study Completion Date

August 31, 2013

Conditions
Partial Epilepsies
Interventions
DRUG

Lacosamide

"Oral Lacosamide:~Subjects Titration Phase (6 Weeks):~Week 1 - 50 mg tablet Twice daily (bid); Week 2 - 100 mg tablet bid; Week 3 - 150 mg tablet bid; Week 4 - 200 mg tablet bid; Week 5 - 200 mg tablet bid; Week 6 - 150 mg tablet bid OR Week 6 - 200 mg tablet bid~Maintenance Phase (24 Weeks):~200 mg tablet bid OR 150 mg tablet bid~Taper Phase (1 - 3 Weeks):~50 mg tablet bid for 1 week OR 100 mg tablet bid for 1 week OR 150 mg tablet bid for 1 week"

Trial Locations (109)

Unknown

103, Irvine

123, Rancho Mirage

156, Clearwater

157, Destin

140, Hollywood

161, Ocala

108, Atlanta

112, Atlanta

124, Augusta

115, Macon

118, Rome

128, Flossmoor

130, Des Moines

102, Bowling Green

117, Paducah

107, Houma

145, Ruston

101, Annapolis

162, Waldorf

153, Boston

136, Pittsfield

144, Springfield

151, Kansas City

114, Paterson

109, Brooklyn

133, Brooklyn

127, West Seneca

158, Charlotte

139, Bismarck

134, Akron

150, Canton

141, Tulsa

121, Indiana

120, Columbia

149, Orangeburg

152, Spartanburg

148, Austin

154, Dallas

146, Tomball

119, Fredericksburg

503, Vienna

703, Blagoevrad

706, Pleven

700, Sofia

702, Sofia

704, Sofia

705, Sofia

707, Sofia

708, Sofia

701, Varna

736, Hradec Králové

735, Litoměřice

733, Ostrava

732, Ostrava-Hrabuvka

737, Prague

734, Trutnov

930, Aarhus

400, Helsinki

402, Oulu

401, Tampere

610, Strasbourg

611, Toulon

521, Athens

520, Thessaloniki

552, Faenza

546, Gallarate

541, Napoli

559, Pietra Ligure

557, Prato

540, Roma

549, Roma

542, Taranto

547, Torino

551, Trieste

180, Aguascalientes

183, Chihuahua City

185, Chihuahua City

184, Ciudad Juárez

189, Guadalajara

181, Mexico City

193, Mexico City

195, Mexico City

186, Monterrey

187, Monterrey

188, Monterrey

182, Polanco

815, Bucharest

810, Cluj-Napoca

814, Oradea

813, Târgu Mureş

830, Kazan'

831, Kazan'

834, Moscow

833, Novosibirsk

598, Terrassa

592, Almería

597, Bajo Sevilla

590, Barcelona

596, Santiago de Compostela

594, Valencia

599, Valladolid

892, Lausanne

713, Adana

714, Ankara

710, Eskişehir

711, Istanbul

719, Istanbul

717, Izmir

718, Trabzon

Sponsors

Lead Sponsor

All Listed Sponsors
lead

UCB Pharma

INDUSTRY

NCT00955357 - Trial to Assess Lacosamide as the First add-on Anti-epileptic Drug Treatment in Patients With Partial-onset Seizures | Biotech Hunter | Biotech Hunter