The Genetics of Evoked Responses to Niacin and Endotoxemia: The GENE Study

NACompletedINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

June 30, 2007

Primary Completion Date

February 28, 2011

Study Completion Date

February 28, 2011

Conditions
Healthy Volunteers
Interventions
DRUG

Immediate Release Niacin, Extended Release Niacin, Endotoxin

Subjects receive a one-time 1000mg dose of immediate release Niacin (Niacor pills), a one-time 1000mg dose of extended release Niacin (Niaspan pill) and one-time 1ng/kg injection of endotoxin (LPS).

Trial Locations (1)

19104

University of Pennsylvania, Philadelphia

All Listed Sponsors
lead

University of Pennsylvania

OTHER

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