Prophylaxis to Reduce Postoperative Atrial Fibrillation in Cardiac Surgery

PHASE3CompletedINTERVENTIONAL
Enrollment

304

Participants

Timeline

Start Date

August 31, 2009

Primary Completion Date

January 31, 2012

Study Completion Date

February 29, 2012

Conditions
Atrial FibrillationAtrial Flutter
Interventions
DRUG

beta blockers

metoprolol 25mg by mouth every 6 hours

DRUG

amiodarone

amiodarone 600mg by mouth evening before surgery amiodarone 600mg by mouth morning of surgery amiodarone 400mg by mouth every 12 hours for 3 days postoperatively

DRUG

ascorbic acid

ascorbic acid 2,000mg by mouth evening before surgery ascorbic acid 2,000mg by mouth morning of surgery ascorbic acid 1,000mg by mouth every 12 hours for 5 postoperative days

Trial Locations (1)

04102

Maine Medical Center, Portland

Sponsors

Lead Sponsor

All Listed Sponsors
lead

MaineHealth

OTHER