A Double Blind Randomised Study of Lapatinib and Placebo in Metastatic TCC of the Urothelium

PHASE2/PHASE3UnknownINTERVENTIONAL
Enrollment

204

Participants

Timeline

Start Date

March 31, 2009

Primary Completion Date

July 31, 2015

Conditions
Bladder Cancer
Interventions
DRUG

lapatinib ditosylate

Given orally

OTHER

Placebo

Given orally

Trial Locations (27)

EC1M 6BQ

Barts and the London NHS Trust, London

Unknown

NHS Grampian - Aberdeen Royal Infirmary, Aberdeen

Basildon and Thurrock University Hospital NHS Trust - Basildon Hospital, Basildon

University Hospitals Birmingham NHS Foundation Trust - Birmingham University Hospital, Birmingham

Royal Bournemouth and Christchurch NHS Foundation Trust - Royal Bournemouth Hospital, Bournemouth

University Hospitals Bristol NHS Trust - Bristol University Hospital, Bristol

Cambridge University Hospitals NHS Trust - Addenbrooke's Hospital, Cambridge

Mid Essex NHS Trust - Broomfield Hospital, Chelmsford

Colchester University Hospitals NHS Trust, Colchester

University Hospitals Coventry & Warwickshire NHS Trust, Coventry

Derby Hospitals NHS Trust - Royal Derby Hospital, Derby

NHS Greater Glasgow and Clyde - The Beatson, Glasgow

Calderdale and Huddersfield NHS Trust - Huddersfield Royal Infirmary, Huddersfield

Ipswich Hospital NHS Trust, Ipswich

University Hospitals of Leicester NHS Trust, Leicester

Clatterbridge Centre for Oncology NHS Trust, Liverpool

Guys & St Thomas' Hospital NHS Trust - Guys Hospital, London

Imperial Healthcare NHS Trust, London

Royal Marsden NHS Trust, London

South Tees NHS Trust - James Cook University Hospital, Middlesbrough

Newcastle Upon Tyne Hospitals NHS Trust, Newcastle

Northampton General Hospitals NHS Trust, Northampton

Nottingham University Hospitals NHS Trust, Nottingham

Sherwood Forest Hospitals NHS Trust - Kings Mill Hospital, Nottingham

Portsmouth Hospitals NHS Trust - Queen Alexandra Hospital, Portsmouth

Barking, Havering and Redbridge NHS Trust - Queens Hospital, Romford

Taunton and Somerset NHS Trust - Musgrove Park Hospital, Taunton

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

GlaxoSmithKline

INDUSTRY

lead

Queen Mary University of London

OTHER