Trial of Linaclotide Administered to Patients With Irritable Bowel Syndrome With Constipation

PHASE3CompletedINTERVENTIONAL
Enrollment

803

Participants

Timeline

Start Date

July 31, 2009

Primary Completion Date

July 31, 2010

Study Completion Date

August 31, 2010

Conditions
Irritable Bowel Syndrome Characterized by Constipation
Interventions
DRUG

Linaclotide 290 micrograms

Oral, once daily each morning at least 30 minutes before breakfast for the duration of the study

DRUG

Matching placebo

Oral, once daily each morning at least 30 minutes before breakfast for the duration of the study

Trial Locations (118)

11021

Forest Investigative Site 017, Great Neck

11023

Forest Investigative Site 011, Great Neck

11214

Forest Investigative Site 035, Brooklyn

11733

Forest Investigative Site 134, Setauket

15206

Forest Investigative Site 039, Pittsburgh

20815

Forest Investigative Site 013, Chevy Chase

21093

Forest Investigative Site 073, Lutherville

21742

Forest Investigative Site 006, Hagerstown

22911

Forest Investigative Site 054, Charlottesville

23294

Forest Investigative Site 050, Richmond

23502

Forest Investigative Site 060, Norfolk

23507

Forest Investigative Site 075, Norfolk

23606

Forest Investigative Site 007, Newport News

24073

Forest Investigative Site 061, Christianburg

27103

Forest Investigative Site 065, Winston-Salem

27403

Forest Investigative Site 016, Greensboro

27612

Forest Investigative Site 088, Raleigh

28304

Forest Investigative Site 072, Fayetteville

28401

Forest Investigative Site 056, Wilmington

28601

Forest Investigative Site 119, Hickory

28607

Forest Investigative Site 122, Boone

29615

Forest Investigative Site 121, Greenville

29651

Forest Investigative Site 069, Greer

Forest Investigative Site 131, Greer

30060

Forest Investigative Site 033, Marietta

30067

Forest Investigative Site 020, Marietta

30189

Forest Investigative Site 040, Woodstock

30342

Forest Investigative Site 032, Atlanta

Forest Investigative Site 103, Atlanta

32168

Forest Investigative Site 129, New Smyrna Beach

32405

Forest Investigative Site 038, Panama City

32806

Forest Investigative Site 092, Orlando

33024

Forest Investigative Site 027, Pembroke Pines

33126

Forest Investigative Site 133, Miami

33143

Forest Investigative Site 031, Miami

33458

Forest Investigative Site 030, Jupiter

33486

Forest Investigative Site 042, Boca Raton

33511

Forest Investigative Site 137, Brandon

33542

Forest Investigative Site 068, Zephyrhills

33606

Forest Investigative Site 015, Tampa

33709

Forest Investigative Site 045, St. Petersburg

33916

Forest Investigative Site 018, Fort Myers

34203

Forest Investigative Site 003, Bradenton

34471

Forest Investigative Site 108, Ocala

34613

Forest Investigative Site 070, Brooksville

34655

Forest Investigative Site 104, Trinity

34741

Forest Investigative Site 077, Kissimmee

35023

Forest Investigative Site 135, Hueytown

35209

Forest Investigative Site 037, Birmingham

35215

Forest Investigative Site 036, Birmingham

35801

Forest Investigative Site 014, Huntsville

37205

Forest Investigative Site 025, Nashville

40509

Forest Investigative Site 067, Lexington

42431

Forest Investigative Site 114, Madisonville

43215

Forest Investigative Site 123, Columbus

44122

Forest Investigative Site 044, Cleveland

45219

Forest Investigative Site 028, Cincinnati

45432

Forest Investigative Site 130, Dayton

47714

Forest Investigative Site 047, Evansville

49048

Forest Investigative Site 125, Kalamazoo

52242

Forest Investigative Site 046, Iowa City

53209

Forest Investigative Site 083, Milwaukee

55318

Forest Investigative Site 064, Chaska

61107

Forest Investigative Site 043, Rockford

63128

Forest Investigative Site 004, St Louis

67005

Forest Investigative Site 029, Arkansas City

67114

Forest Investigative Site 009, Newton

67205

Forest Investigative Site 023, Wichita

67207

Forest Investigative Site 093, Wichita

70808

Forest Investigative Site 132, Baton Rouge

71101

Forest Investigative Site 124, Shreveport

73104

Forest Investigative Site 082, Oklahoma City

74135

Forest Investigative Site 102, Tulsa

75234

Forest Investigative Site 002, Dallas

77090

Forest Investigative Site 041, Houston

Forest Investigative Site 110, Houston

77566

Forest Investigative Site 063, Lake Jackson

78209

Forest Investigative Site 095, San Antonio

78229

Forest Investigative Site 076, San Antonio

78705

Forest Investigative Site 099, Austin

80033

Forest Investigative Site 010, Wheat Ridge

80205

Forest Investigative Site 034, Denver

80304

Forest Investigative Site 021, Boulder

80501

Forest Investigative Site 074, Longmont

80907

Forest Investigative Site 019, Colorado Springs

83404

Forest Investigative Site 055, Idaho Falls

84102

Forest Investigative Site 089, Salt Lake City

84132

Forest Investigative Site 091, Salt Lake City

84148

Forest Investigative Site 100, Salt Lake City

85012

Forest Investigative Site 101, Phoenix

85018

Forest Investigative Site 128, Phoenix

85210

Forest Investigative Site 053, Mesa

85225

Forest Investigative Site 080, Chandler

85251

Forest Investigative Site 051, Scottsdale

85381

Forest Investigative Site 078, Peoria

85712

Forest Investigative Site 136, Tucson

85741

Forest Investigative Site 087, Tucson

87106

Forest Investigative Site 052, Albuquerque

90036

Forest Investigative Site 057, Los Angeles

91345

Forest Investigative Site 097, Mission Hills

91361

Forest Investigative Site 024, Westlake Village

91505

Forest Investigative Site 094, Burbank

92024

Forest Investigative Site 026, Encinitas

92610

Forest Investigative Site 096, Foothill Ranch

92869

Forest Investigative Site 005, Orange

98402

Forest Investigative Site 049, Bellevue

98499

Forest Investigative Site 098, Lakewood

98801

Forest Investigative Site 066, Wenatchee

06708

Forest Investigative Site 058, Waterbury

02135

Forest Investigative Site 001, Boston

08360

Forest Investigative Site 085, Vineland

P3E 1H5

Forest Investigative Site 113, Greater Sudbury

L8N 4A6

Forest Investigative Site 107, Hamilton

L3Y 7V1

Forest Investigative Site 112, Newmarket

K2C 3R2

Forest Investigative Site 106, Ottawa

N7T 4X3

Forest Investigative Site 115, Sarnia

M3N 2V7

Forest Investigative Site 008, Toronto

M4S 1Y2

Forest Investigative Site 116, Toronto

Sponsors
All Listed Sponsors
collaborator

Ironwood Pharmaceuticals, Inc.

INDUSTRY

lead

Forest Laboratories

INDUSTRY