Modafinil in the Treatment of Fatigue in Patients With Primary Biliary Cirrhosis (PBC)

PHASE1CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

June 30, 2009

Primary Completion Date

April 30, 2011

Study Completion Date

April 30, 2011

Conditions
FatiguePrimary Biliary Cirrhosis
Interventions
DRUG

Modafinil

100 mg tablets of modafinil or matched placebo will be given for a total of 12 weeks. Patients will be instructed to start one capsule once daily (modafinil or placebo), and dose will be titrated according to tolerability and response.

Trial Locations (1)

55905

Mayo Clinic, Rochester

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

American College of Gastroenterology

OTHER

lead

Mayo Clinic

OTHER