Comparing the Effects of Conivaptan and Diuretics on Plasma Neurohormones and Renal Blood Flow in Patients With Chronic Congestive Heart Failure

NAUnknownINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

July 31, 2009

Primary Completion Date

December 31, 2009

Study Completion Date

March 31, 2010

Conditions
Heart Failure
Interventions
DRUG

Conivaptan

Conivaptan 20 mg IV bolus followed by a 4 hour infusion at 1.2 mg/hr

DRUG

Furosemide

Furosemide will be given IV at the subjects usual oral dose up to 80 mg. If the dose is 80 mg or more only 1/2 the dose will be given IV.

DRUG

Conivaptan and furosemide

Furosemide bolus first; conivaptan 20 mg IV bolus/infusion at 1.2 mg/hour for a total of 4 hours

Trial Locations (1)

55404

Hennepin county Medical Center, Minneapolis

Sponsors

Collaborators (1)

All Listed Sponsors
lead

Hennepin County Medical Center, Minneapolis

OTHER

collaborator

Astellas Pharma Inc

INDUSTRY