260
Participants
Start Date
May 31, 2009
Primary Completion Date
December 31, 2015
Study Completion Date
December 31, 2015
Catheter Ablation
Intracardiac electrode catheters are placed via central vasculature to identify myocardial scar, and surviving conduction channels within the scar which form the substrate for ventricular tachycardia. Radiofrequency energy is applied to these sites, interrupting the VT circuits.
Escalated Antiarrhythmic Therapy
"Patients who have 'failed' antiarrhythmic therapy (except amiodarone) will be prescribed: Amiodarone 400 mg twice daily for 2 weeks, followed by 400 mg/day for 4 weeks, followed by 200 mg/day thereafter.~Patients who 'failed' amiodarone (less than 300mg/day) will be prescribed: Amiodarone 400 mg three times a day for 2 weeks, followed by 400 mg/day for 1 week and 300 mg/day thereafter.~Patients who 'failed' amiodarone (greater or equal to 300mg/day) will be prescribed: Amiodarone at the current dose with the addition of mexiletine 400 to 800 mg/day"
QEII Health Sciences Centre, Halifax
Collaborators (1)
Abbott Medical Devices
INDUSTRY
Biosense Webster, Inc.
INDUSTRY
Canadian Institutes of Health Research (CIHR)
OTHER_GOV
John Sapp
OTHER