NCT00895895View on ClinicalTrials.gov

Study Comparing 3 Dosage Levels Of SAM-531 In Outpatients With Mild To Moderate Alzheimer Disease

PHASE2TerminatedINTERVENTIONAL
Enrollment

526

Participants

Timeline

Start Date

May 31, 2009

Primary Completion Date

May 31, 2011

Study Completion Date

May 31, 2011

Conditions
Alzheimer Disease
Interventions
DRUG

Placebo

Capsules SAM-531 placebo and 5 mg tablet encapsulated Donepezil placebo capsules, once a day during 24 weeks.

DRUG

SAM-531 1.5 mg

Capsules SAM-531 1.5 mg, once a day during 52 weeks.

DRUG

SAM-531 3.0 mg

Capsules SAM-531 3.0 mg, once a day during 52 weeks.

DRUG

SAM-531 5.0 mg

Capsules SAM-531 5.0 mg, once a day during 24 weeks or 52 weeks.

DRUG

Donepezil

Encapsulated Donepezil 5 mg tablets, once a day during 52 weeks. After Day 42, the dose can up titrated up to 10 mg of Donepezil.

Trial Locations (96)

1022

Pfizer Investigational Site, Caba

Pfizer Investigational Site, Ciudad de Buenos Aires

2196

Pfizer Investigational Site, Johannesburg

3240

Pfizer Investigational Site, Hamilton

7530

Pfizer Investigational Site, Bellville

Pfizer Investigational Site, Cape Town

9301

Pfizer Investigational Site, Bloemfontein

10312

Pfizer Investigational Site, Staten Island

11516

Pfizer Investigational Site, Cedarhurst

18104

Pfizer Investigational Site, Allentown

20127

Pfizer Investigational Site, Aguascalientes

25000

Pfizer Investigational Site, Saltillo

30308

Pfizer Investigational Site, Atlanta

33009

Pfizer Investigational Site, Hallandale

33180

Pfizer Investigational Site, Miami

33317

Pfizer Investigational Site, Plantation

33351

Pfizer Investigational Site, Sunrise

33407

Pfizer Investigational Site, West Palm Beach

33462

Pfizer Investigational Site, Atlantis

33613

Pfizer Investigational Site, Tampa

33702

Pfizer Investigational Site, St. Petersburg

33709

Pfizer Investigational Site, St. Petersburg

34102

Pfizer Investigational Site, Naples

34601

Pfizer Investigational Site, Brooksville

37067

Pfizer Investigational Site, Franklin

43623

Pfizer Investigational Site, Toledo

53562

Pfizer Investigational Site, Middleton

60007

Pfizer Investigational Site, Elk Grove Village

60068

Pfizer Investigational Site, Park Ridge

63104

Pfizer Investigational Site, St Louis

63110

Pfizer Investigational Site, St Louis

73103

Pfizer Investigational Site, Oklahoma City

73112

Pfizer Investigational Site, Oklahoma City

73116

Pfizer Investigational Site, Oklahoma City

74104

Pfizer Investigational Site, Tulsa

80218

Pfizer Investigational Site, Denver

80239

Pfizer Investigational Site, Denver

85004

Pfizer Investigational Site, Phoenix

85050

Pfizer Investigational Site, Phoenix

90806

Pfizer Investigational Site, Long Beach

92626

Pfizer Investigational Site, Costa Mesa

92845

Pfizer Investigational Site, Garden Grove

93030

Pfizer Investigational Site, Oxnard

93720

Pfizer Investigational Site, Fresno

97210

Pfizer Investigational Site, Portland

115522

Pfizer Investigational Site, Moscow

123182

Pfizer Investigational Site, Moscow

150030

Pfizer Investigational Site, Yaroslavl

188357

Pfizer Investigational Site, Nikolskoe Village

190005

Pfizer Investigational Site, Saint Petersburg

192019

Pfizer Investigational Site, Saint Petersburg

194044

Pfizer Investigational Site, Saint Petersburg

197022

Pfizer Investigational Site, Saint Petersburg

198103

Pfizer Investigational Site, Saint Petersburg

200317

Pfizer Investigational Site, Craiova

214018

Pfizer Investigational Site, Smolensk

300736

Pfizer Investigational Site, Timișoara

420101

Pfizer Investigational Site, Kazan'

630054

Pfizer Investigational Site, Novosibirsk

2520997

Pfizer Investigational Site, Viña del Mar

7500922

Pfizer Investigational Site, Santiago

7530193

Pfizer Investigational Site, Santiago

7630000

Pfizer Investigational Site, Santiago

8330838

Pfizer Investigational Site, Santiago

05201

Pfizer Investigational Site, Bennington

C1126AAB

Pfizer Investigational Site, C.a.b.a.

C1425BWO

Pfizer Investigational Site, Ciudad de Buenos Aires

Unknown

Pfizer Investigational Site, Bogota

Pfizer Investigational Site, Pereira

Pfizer Investigational Site, Bucamaranga

Pfizer Investigational Site, Santiago de Cali

Pfizer Investigational Site, Valle Del Cauca

Pfizer Investigational Site, Shatin, N.T.

Pfizer Investigational Site, Hong Kong

Pfizer Investigational Site, Hachiōji

Pfizer Investigational Site, Chiba

Pfizer Investigational Site, Fukuoka

Pfizer Investigational Site, Hiroshima

Pfizer Investigational Site, Kanagawa

Pfizer Investigational Site, Kumamoto

Pfizer Investigational Site, Kyoto

Pfizer Investigational Site, Nagano

Pfizer Investigational Site, Nagasaki

Pfizer Investigational Site, Shizuoka

0622

Pfizer Investigational Site, Auckland

31-531

Pfizer Investigational Site, Krakow

Pfizer Investigational Site, Krakow

61-289

Pfizer Investigational Site, Poznan

50-088

Pfizer Investigational Site, Wroclaw

010825

Pfizer Investigational Site, Bucharest

011241

Pfizer Investigational Site, Bucharest

041914

Pfizer Investigational Site, Bucharest

050098

Pfizer Investigational Site, Bucharest

0041

Pfizer Investigational Site, Pretoria

463-707

Pfizer Investigational Site, Seongnam-si

138-736

Pfizer Investigational Site, Seoul

Sponsors

Lead Sponsor

Pfizer
All Listed Sponsors
lead

Pfizer

INDUSTRY