NCT00880373View on ClinicalTrials.gov

Ibuprofen and Opioid (Morphine or Diamorphine) for Acute Pain in Sickle Cell Disease - Sickle With Ibuprofen & Morphine

PHASE4TerminatedINTERVENTIONAL
Enrollment

320

Participants

Timeline

Start Date

March 31, 2011

Primary Completion Date

March 31, 2014

Study Completion Date

August 31, 2014

Conditions
Sickle Cell Disease
Interventions
DRUG

Ibuprofen

Oral ibuprofen 800 mg three times daily for a total of 2400 mg per day for 4 days

DRUG

Placebo

Matching placebo three times daily for 4 days

DRUG

Diamorphine or Morphine

Diamorphine or Morphine by PCA

Trial Locations (2)

NW10 7NS

North West London Hospitals NHS Trust, London

W12 0HS

Imperial College Healthcare NHS Trust, London

Sponsors
All Listed Sponsors
collaborator

Medical Research Council CTU

UNKNOWN

lead

London North West Healthcare NHS Trust

OTHER