Study to Evaluate Analgesic Effect of Intravenous Administration of Kappa Agonist CR845 After Hysterectomy Surgery

PHASE2CompletedINTERVENTIONAL
Enrollment

114

Participants

Timeline

Start Date

March 31, 2009

Primary Completion Date

December 31, 2009

Study Completion Date

January 31, 2010

Conditions
Acute Pain
Interventions
DRUG

CR845

CR845 (0.024 mg/kg) administered the day after surgery (Day 1)

DRUG

CR845

CR845 (0.008 mg/kg) administered the day after surgery (Day 1)

DRUG

CR845

CR845 (0.040 mg/kg) administered immediately after surgery (Day 0)

DRUG

Placebo

Matched placebo administered the day after surgery (Day 1)

DRUG

Placebo

Matched placebo administered immediately after surgery (Day 0)

Trial Locations (12)

33136

University of Miami/Jackson Memorial Hospital, Miami

33472

Palms West Hospital, Loxahatchee Groves

35660

Helen Keller Hospital, Sheffield

36607

Mobile Infirmary Medical Center, Mobile

36608

Springhill Medical Center, Mobile

43210

The Ohio State University Medical Center, Columbus

77024

Memorial Hermann - Memorial City Medical Center, Houston

77054

The Woman's Hospital of Texas, Houston

85032

Paradise Valley Hospital, Phoenix

91105

Huntington Memorial Hospital, Pasadena

91206

Adventist Medical Center, Glendale

92653

Saddleback Memorial Hospital, Laguna Hills

Sponsors
All Listed Sponsors
lead

Cara Therapeutics, Inc.

INDUSTRY