Effectiveness and Safety of Atypical Antipsychotic Agents in Augmenting SSRI-Refractory Obsessive-Compulsive Disorder

PHASE4CompletedINTERVENTIONAL
Timeline

Start Date

January 31, 2006

Primary Completion Date

December 31, 2007

Study Completion Date

December 31, 2007

Conditions
SSRI-Refractory Obsessive-Compulsive Disorder
Interventions
DRUG

atypical antipsychotic drug

For SSRI-refractory group, either atypical antipsychotic such as mean doses of RIS (3.1±1.9mg/day), of OLZ (5.1±3.2mg/day), and of QET (60.0±37.3mg/day) was added on ongoing SSRI(Paroxetine, Fluvoxamine).

BEHAVIORAL

exposure response prevention

After at least 12 weeks from treatment initiation, cognitive-behavioral therapy (CBT) using exposure and response prevention was added with psychoeducational interventions and behavioral analysis.

Trial Locations (1)

545-8585

Dept of Neuropsychiatry, Osaka City University, graduate School of Medicine, Osaka

All Listed Sponsors
lead

Osaka City University

OTHER

NCT00854919 - Effectiveness and Safety of Atypical Antipsychotic Agents in Augmenting SSRI-Refractory Obsessive-Compulsive Disorder | Biotech Hunter | Biotech Hunter