Stereotactic Radiosurgery in Treating Patients With Spinal Metastases

PHASE1CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

January 31, 2009

Primary Completion Date

June 30, 2013

Study Completion Date

June 30, 2017

Conditions
Metastatic Cancer
Interventions
OTHER

questionnaire administration

prior to radiosurgery, at radiosurgery completion, and then at subsequent follow-ups (3, 6, 9, 12, 18, and 24 months after treatment

PROCEDURE

diffusion tensor imaging

prior to initiating CyberKnife radiosurgery, at 6 weeks after CyberKnife therapy, and at 6 months after CyberKnife therapy

PROCEDURE

functional magnetic resonance imaging

prior to CyberKnife, at 6 weeks, and 3 months after CyberKnife?, every 3 months for the first year, and every 6 months thereafter

RADIATION

hypo-fractionated SRS

two to three consecutive daily sessions within one week for 3 cohorts- Cohort 1 = 21 Gy; Cohort 2 = 24 Gy; Cohort 3 = 27 Gy

RADIATION

single-fraction SRS

two to three consecutive daily sessions within one week for 3 cohorts- for 3 cohorts- Cohort 1 = 16 Gy; Cohort 2 = 18 Gy; Cohort 3 = 20 Gy

Trial Locations (1)

02118

Boston University Cancer Research Center, Boston

Sponsors
All Listed Sponsors
collaborator

United States Department of Defense

FED

lead

Boston Medical Center

OTHER