1,015
Participants
Start Date
September 30, 2009
Primary Completion Date
April 30, 2013
Study Completion Date
November 30, 2013
Genotype-guided dosing algorithm for warfarin
Initial dosing of warfarin for the first 3-4 days of treatment will be determined by an algorithm that uses clinical and genetic information. Following this initiation dose of warfarin, a second dose adjustment will be made after 3 and/or 4 doses of warfarin using a dose revision algorithm that incorporates the clinical and genetic information.
Clinical-guided dosing algorithm for warfarin
Initial dosing of warfarin for the first 3-4 days of treatment will be determined by an algorithm that uses clinical information. Following this initiation dose of warfarin, a second dose adjustment will be made after 3 and/or 4 doses of warfarin using a dose revision algorithm that incorporates the clinical information.
Mount Sinai School of Medicine, New York
Montefiore Medical Center, The Bronx
Hospital of the University of Pennsylvania, Philadelphia
University of Maryland School of Medicine, Baltimore
Duke University, Durham
Georgia Health Sciences University, Augusta
University of Alabama at Birmingham, Birmingham
Vanderbilt University, Nashville
Henry Ford Hospital, Detroit
Marshfield Clinical Research Foundation, Marshfield
Mayo Clinic College of Medicine, Rochester
Washington University School of Medicine, St Louis
Tulane University Health Science Center, New Orleans
University of Texas Medical Branch, Galveston
University of Utah Health Care, Salt Lake City
University of California San Francisco, San Francisco
University of Florida, Gainesville
Intermountain Medical Center, Murray
Collaborators (1)
Bristol-Myers Squibb
INDUSTRY
National Heart, Lung, and Blood Institute (NHLBI)
NIH