Oral Aprepitant and Lower Dose Dexamethasone Versus Aprepitant Alone for Preventing Postoperative Nausea and Vomiting (PONV) After Elective Laparoscopic Surgeries

NAUnknownINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

February 28, 2009

Primary Completion Date

December 31, 2009

Conditions
NauseaVomiting
Interventions
DRUG

Dexamethasone

Dexamethasone 5 mg administered intravenously following endotracheal intubation

DRUG

Aprepitant

Aprepitant 40mg PO one time at least one hour prior to induction of anesthesia

DRUG

Placebo Dexamethasone

Trial Locations (1)

19096

Lankenau Hospital, Wynnewood

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

collaborator

Drexel University College of Medicine

OTHER

lead

Main Line Health

OTHER