Positron Emission Tomography (PET) Study With [11C]Raclopride to Determine Central D2 Dopamine Occupancy of SEROQUEL

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

January 31, 2009

Study Completion Date

September 30, 2009

Conditions

Depression

Interventions

DRUG

SEROQUEL XR (quetiapine)

repeated dose of oral tablets, 8 times per subject

DRUG

SEROQUEL IR (quetiapine)

repeated dose of oral tablets, 4 times per subject

DRUG

radioligand [11C]raclopride

single dose of iv admin, 5 times per subject

Trial Locations (1)

Research Site, Stockholm