Study of Cilostazol and Probucol Alone and in Combination on Atherosclerosis Related Biomarker---atherosclerosis Cerebral Infarction Patient as Study Subject

PHASE4CompletedINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

March 31, 2009

Primary Completion Date

December 31, 2009

Study Completion Date

July 31, 2010

Conditions
Atherosclerosis Cerebral Infarction
Interventions
DRUG

Cilostazol group

Cilostazol: At first, 50 mg (1 tablets) Bid, PO after breakfast and dinner. After administration of study drug for 1 week, and if patient has no significant discomfort, the drug dosage will increase to 100mg(2 tablets)Bid.

DRUG

Probucol group

Probucol: 250 mg (1 tablet) Bid, PO after breakfast and dinner

DRUG

Cilostazol + Probucol group

"Cilostazol: At first, 50 mg (1 tablets) Bid, PO after breakfast and dinner. After administration of study drug for 1 week, and if patient has no significant discomfort, the drug dosage will increase to 100mg(2 tablets)Bid.~Probucol: 250 mg (1 tablet) Bid, PO after breakfast and dinner"

DRUG

control group

routine treatment

Trial Locations (1)

Unknown

First Affliate Hospital of Beijing University, Beijing

All Listed Sponsors
lead

Otsuka Beijing Research Institute

INDUSTRY