A Study of Avastin (Bevacizumab) in Patients With Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

PHASE3CompletedINTERVENTIONAL
Enrollment

1,044

Participants

Timeline

Start Date

February 28, 2005

Primary Completion Date

February 28, 2011

Study Completion Date

February 28, 2011

Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
DRUG

Cisplatin

80mg/m2 iv on day 1 of each 3 week cycle, for a maximum of 6 cycles

DRUG

Gemcitabine

1250mg/m2 on days 1 and 8 of each 3 week cycle for a maximum of 6 cycles

DRUG

Placebo

iv on day 1 of each 3 week cycle until disease progression

DRUG

bevacizumab [Avastin]

15mg/kg 1v on day 1 of each 3 week cycle until disease progression

DRUG

bevacizumab [Avastin]

7.5 mg/kg iv on day 1 of each 3 week cycle until disease progression

Trial Locations (154)

105

Taipei

333

Kueishan

404

Taichung

407

Taichung

852

Hong Kong

1200

Brussels

1527

Sofia

1529

Budapest

1756

Sofia

2000

Santa Fe

2050

Sydney

2139

Sydney

2500

Wollongong

2606

Canberra

3000

Leuven

3052

Parkville

3128

Melbourne

4000

San Miguel de Tucumán

Liège

4004

Plovdiv

4029

Brisbane

4224

Tugun

4400

Nyíregyháza

5000

Veliko Tarnovo

5011

Adelaide

5037

Kurralta Park

5065

Adelaide

5500

Mendoza

6009

Perth

7100

Haine-Saint-Paul

7257

Mosdós

8000

Bahía Blanca

Stara Zagora

8001

Székesfehérvár

8901

Zalaegerszeg

9002

Varna

9700

Szombathely

10060

Candiolo

10400

Bangkok

11522

Athens

11527

Athens

13273

Marseille

14076

Caen

14165

Berlin

16132

Genova

17007

Girona

20089

Rozzano

20133

Milan

20162

Milan

20246

Hamburg

21075

Hamburg

22045

Hamburg

25209

Montbéliard

28040

Madrid

28041

Madrid

28046

Madrid

28222

Madrid

29010

Málaga

34295

Montpellier

35033

Rennes

37075

Göttingen

38320

San Cristóbal de La Laguna

41013

Seville

41014

Seville

Valencia

42100

Reggio Emilia

43100

Parma

44281

Kfar Saba

44805

Saint-Herblain

45122

Essen

46009

Valencia

46010

Valencia

46015

Valencia

48903

Barakaldo

49100

Petah Tikva

50200

Chiang Mai

51375

Leverkusen

52621

Ramat Gan

54511

Vandœuvre-lès-Nancy

55131

Mainz

57010

Thessaloniki

58675

Hemer

67091

Strasbourg

68100

Alexandroupoli

68167

Mannheim

69004

Lyon

69126

Heidelberg

69495

Pierre-Bénite

76000

Rouen

76137

Karlsruhe

80131

Napoli

80336

München

82131

Gauting

90016

Belfort

91120

Jerusalem

93009

Bobigny

95123

Catania

105229

Moscow

107005

Moscow

115478

Moscow

123098

Moscow

143423

Moscow

143900

Balashikha

197089

Saint Petersburg

197758

Saint Petersburg

198255

Saint Petersburg

6423906

Tel Aviv

30150321

Belo Horizonte

C1270AAE

Buenos Aires

C1426ANZ

Buenos Aires

03000

Santa Fe

90020-090

Porto Alegre

20231-050

Rio de Janeiro

01221-020

São Paulo

T2N 4N2

Calgary

T6G 1Z2

Edmonton

V8R 6V5

Victoria

E1C 8X3

Moncton

N6A 4L6

London

L5M 2N1

Mississauga

L3Y 2P9

Newmarket

M5G 1X5

Toronto

M5G 2M9

Toronto

M9N 1N8

Toronto

J4V 2H1

Greenfield Park

H2L 4M1

Montreal

H2W 1S6

Montreal

G1V 4G2

Sainte-Foy

703 84

Ostrava

708 52

Ostrava

180 01

Prague

401 13

Ústí nad Labem

Unknown

Hong Kong

Taipei

06132

Perugia

00152

Roma

00168

Roma

80-214

Gdansk

81-519

Gdynia

20-950

Lublin

10-228

Olsztyn

60-569

Poznan

70-891

Szczecin

02-781

Warsaw

03010

Alicante

08035

Barcelona

08036

Barcelona

08907

Barcelona

GU2 7XX

Guildford

N18 1QX

London

M2O 4BX

Manchester

S10 2SJ

Sheffield

SM2 5PT

Sutton

BA21 4AT

Yeovil

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY

NCT00806923 - A Study of Avastin (Bevacizumab) in Patients With Non-Squamous Non-Small Cell Lung Cancer (NSCLC) | Biotech Hunter | Biotech Hunter