53
Participants
Start Date
May 31, 2005
Primary Completion Date
June 30, 2012
Study Completion Date
June 30, 2012
Thymoglobulin
"3.5 or 2.5 mg/kg/day IV for 5 days~* Aplastic anemia patients receive 3.5 mg/kg/day for 5 days~* MDS patients \<55 years receive 3.5 mg/kg/day for 5 days~* MDS patients \>55 years receive 2.5 mg/kg/day for 5 days"
Cyclosporine
5 mg/kg orally for 6 months; start after completing thymoglobulin.
Methylprednisolone
1 mg/kg/day IV for 5 days, given before each dose of thymoglobulin.
G-CSF
5 microgram/kg subcutaneously daily up to 3 months, start after thymoglobulin.
UT MD Anderson Cancer Center, Houston
Genzyme, a Sanofi Company
INDUSTRY
M.D. Anderson Cancer Center
OTHER