First-line R-CVP vs R-CHOP Induction Immunochemotherapy for Indolent Lymphoma and R Maintenance.

PHASE3CompletedINTERVENTIONAL
Enrollment

250

Participants

Timeline

Start Date

February 28, 2007

Primary Completion Date

June 25, 2017

Study Completion Date

June 25, 2017

Conditions
Follicular LymphomaMarginal Zone LymphomaSmall Lymphocytic LymphomaLymphoplasmacytic Lymphoma
Interventions
DRUG

Rituximab

Rituximab 375 mg/m2 i.v. d. 1 q. 21 d.

DRUG

Cyclophosphamide

Cyclophosphamide 750 mg/m2 i.v. d. 1 q. 21 d.

DRUG

Doxorubicin

Doxorubicin 50 mg/m2 i.v. d. 1 q. 21 d.

DRUG

Vincristine

Vincristine 1.4 mg/m2 (max. 2 mg) i.v. d. 1 q. 21 d.

DRUG

Prednisone 1

Prednisone 100 mg p.o. d. 1-5 q. 21 d.

DRUG

Prednisone 2

Prednisone 40 mg/m2 p.o. d. 1-5 q. 21 d.

Trial Locations (12)

36-200

Podkarpacki Oncology Centre, Brzozów

82-300

Voivodeship Hospital, Oncology Ward, Elblag

80-211

Academic Clinical Centre, Hospital of Medical Academy, Clinic of Haematology and Transplantology, Gdansk

40-029

Silesian Medical University, Chair and Clinic of Haematology and Bone Marrow Transplantation, Katowice

31-501

Collegium Medicum Jagiellonian University, Clinic of Haematology, Krakow

93-509

Regional Oncology Centre, Ward of Proliferative Diseases, Lodz

20-090

Oncology Centre of Lublin Region, Lublin

02-507

Central Clinical Hospital, Ministry of Internal Matters and Administration; Clinic of Oncology, Haematology and Internal Diseases, Warsaw

02-776

Institute of Haematology and Transfusiology, Warsaw

02-782

M.Sklodowska-Curie Institute - Oncology Centre, Warsaw

50-367

Medical Academy in Wrocław; Chair and Clinic of Haematology, Blood Neoplasm and Bone Marrow Transplantation, Wroclaw

53-439

SP ZOZ Silesian Centre of Cellular Transplantation, Wroclaw

All Listed Sponsors
lead

Polish Lymphoma Research Group

NETWORK

NCT00801281 - First-line R-CVP vs R-CHOP Induction Immunochemotherapy for Indolent Lymphoma and R Maintenance. | Biotech Hunter | Biotech Hunter