80
Participants
Start Date
January 31, 2005
Primary Completion Date
December 31, 2008
Study Completion Date
January 31, 2009
Sodium Butyrate
Patients will be instructed to lie on a bed (cholera cot) in left lateral position. A soft rectal catheter will be introduced by a nurse/physician, through which 80 ml of butyrate solution will be instilled slowly with a 50 ml plastic syringe. Patients will be asked to retain the enema for at least ½ hour by remaining supine for 30 minutes after the administration. However, if a patient cannot retain the enema for 30 minutes, he will be given a second round of enema immediately after defecation.
Saline
Patients will be instructed to lie on a bed (cholera cot) in left lateral position. A soft rectal catheter will be introduced by a nurse/physician, through which 80 ml of saline solution will be instilled slowly with a 50 ml plastic syringe. Patients will be asked to retain the enema for at least ½ hour by remaining supine for 30 minutes after the administration. However, if a patient cannot retain the enema for 30 minutes, he will be given a second round of enema immediately after defecation.
Dhaka Hospital & Matlab Hospital, Dhaka
ICDDR,B, Dhaka
Swedish International Development Cooperation Agency (SIDA)
OTHER_GOV
Karolinska Institutet
OTHER
International Centre for Diarrhoeal Disease Research, Bangladesh
OTHER