Effects of Levosimendan on Microcirculation in Septic Shock

PHASE2CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

November 30, 2007

Primary Completion Date

February 29, 2008

Study Completion Date

April 30, 2009

Conditions
Septic Shock
Interventions
DRUG

Levosimendan

Intravenous administration of Levosimendan 0,2 µg•kg-1•min-1 for 24 hrs followed by the addition of 35 ppm of inhaled nitric oxide

DRUG

dobutamine

Intravenous administration of dobutamine 5 µg•kg-1•min-1 for 36 hrs. At the end of the first 24 hrs drug infusion, inhaled nitric oxide at the concentration of 35 ppm will be added for further 12 hrs.

Trial Locations (1)

00161

"Departement of Anesthesiology and Intensive Care of the University of Rome La Sapienza Viale del Policlinico 155", Rome

All Listed Sponsors
lead

University of Roma La Sapienza

OTHER

NCT00800306 - Effects of Levosimendan on Microcirculation in Septic Shock | Biotech Hunter | Biotech Hunter