Local Infiltration Analgesia Following Total Knee Arthroplasty

NACompletedINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

April 30, 2007

Primary Completion Date

June 30, 2008

Study Completion Date

September 30, 2008

Conditions
Postoperative Pain
Interventions
DRUG

ropivacaine, ketorolac and epinephrine

In Group A, 400 mg ropivicaine, 30 mg ketorolac and 0.5 mg epinephrine (total volume 166 ml) are infiltrated by the surgeon into the soft tissues peri-articularly during the operation in the following way: Before inserting the components, 20-30 ml are injected into the posterior capsule and before closure of the wound the rest is injected into the capsule incision, the synovium, the ligament and the subcutaneous tissue. After 21 postoperative hours in Group A, 200 mg ropivicaine, 30 mg ketorolac and 0.1 mg epinephrine, total volume 22 ml, are injected intraarticularly via the catheter.

DRUG

saline

In Group P (placebo) no injections were given intraoperatively. All patients had a tunnelled intra-articular multihole 20-G catheter placed at the end of the operation by the surgeon.After 21 postoperative hours 22 ml of saline was injected intraarticularly via the catheter.

Trial Locations (2)

70185

University Hospital Orebro, Örebro

701 85

University Hospital Orebro, Örebro

All Listed Sponsors
lead

Region Örebro County

OTHER

NCT00799175 - Local Infiltration Analgesia Following Total Knee Arthroplasty | Biotech Hunter | Biotech Hunter