Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis

PHASE3CompletedINTERVENTIONAL
Enrollment

692

Participants

Timeline

Start Date

November 30, 2009

Primary Completion Date

January 31, 2017

Study Completion Date

January 31, 2017

Conditions
Deep Vein ThrombosisVenous ThrombosisPostphlebitic SyndromeVenous ThromboembolismPost Thrombotic Syndrome
Interventions
DRUG

Recombinant tissue plasminogen activator (rt-PA)

Pharmacomechanical catheter-directed thrombolysis, consisting of intrathrombus administration of rt-PA using a catheter/device.

Trial Locations (56)

10021

Cornell Weill Medical Center, New York

10305

Staten Island University Hospital, Staten Island

15212

Allegheny General Hospital, Pittsburgh

15213

University of Pittsburgh Medical Center Presbyterian Shadyside, Pittsburgh

15224

The Western Pennsylvania Hospital, Pittsburgh

18015

St. Luke's Hospital and Health Network, Bethlehem

19141

Albert Einstein Medical Center, Philadelphia

19611

The Reading Hospital and Medical Center, West Reading

19718

Christiana Care Health Systems, Newark

20007

Georgetown University Hospital, Washington D.C.

21201

University of Maryland, Baltimore

22908

University of Virginia Health System, Charlottesville

27103

Forsyth Medical Center, Winston-Salem

27157

Wake Forest University Baptist Medical Center, Winston-Salem

29425

Medical University of South Carolina, Charleston

32803

Florida Hospital, Orlando

33176

Baptist Cardiac & Vascular Institute, Miami

33613

Florida Hospital-Tampa Division-Pepin Heart Institute and Dr. Kiran C. Patel Research Institute, Tampa

33761

Mease Countryside Hospital, Clearwater

41042

St. Elizabeth Healthcare of Northern Kentucky, Florence

43214

Riverside Methodist Hospital, Columbus

43606

Jobst Vascular Center, Toledo

44195

Cleveland Clinic, Cleveland

45220

Good Samaritan Hospital, Cincinnati

46260

CorVasc, Indianapolis

48105

Ann Arbor Veteran's Administration Health System, Ann Arbor

48109

University of Michigan Medical Center, Ann Arbor

48202

Henry Ford Health System, Detroit

52242

University of Iowa Carver's College of Medicine, Iowa City

53226

Medical College of Wisconsin/Froedtert Hospital, Milwaukee

54601

Gundersen Clinic, Ltd., La Crosse

55455

University of Minnesota, Minneapolis

55905

Mayo Clinic, Rochester

60190

Central DuPage Hospital, Winfield

60612

University of Illinois at Chicago, Chicago

62702

Southern Illinois University, Springfield

63110

Washington University School of Medicine, St Louis

64111

St. Luke's Hospital of Kansas City, Kansas City

84132

University of Utah, Salt Lake City

84604

Utah Valley Regional Medical Center, Provo

85306

Arrowhead Hospital/Phoenix Heart, PLLC, Glendale

87131

University of New Mexico, Albuquerque

92868

St. Joseph Hospital, Orange

94305

Stanford University Medical Center, Stanford

97239

Oregon Health & Science University, Portland

99204

Sacred Heart Medical Center, Spokane

06810

Danbury Hospital, Danbury

06360

Eastern Connecticut Hematology and Oncology Associates, Norwich

Unknown

Adventist Midwest Health, Hinsdale

Temple University Hospital, Philadelphia

04102

Maine Medical Center, Portland

02114

Massachusetts General Hospital, Boston

68510-2494

Saint Elizabeth Regional Medical Center, Lincoln

07666

Holy Name Hospital, Teaneck

27599-7035

University of North Carolina at Chapel Hill, Chapel Hill

02903

Rhode Island Hospital, Providence

All Listed Sponsors
collaborator

McMaster University

OTHER

collaborator

Ontario Clinical Oncology Group (OCOG)

OTHER

collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

collaborator

BSN Medical Inc

INDUSTRY

collaborator

Genentech, Inc.

INDUSTRY

collaborator

Medtronic - MITG

INDUSTRY

collaborator

Boston Scientific Corporation

INDUSTRY

collaborator

Mid America Heart Institute

OTHER

collaborator

Society of Interventional Radiology Foundation

OTHER

collaborator

Massachusetts General Hospital

OTHER

lead

Washington University School of Medicine

OTHER